Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 7/20 | 0.36 |
| ▸ | SNCA | P37840 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25517177 | 0.92 | IDO1 (0.33) | BCL2L1MCL1RAB9ANPC1MAPT | |
| SCHEMBL10133862 | 0.89 | BCL2L1 (0.44) | BCL2L1MCL1RAB9ANPC1MAPT | |
| SCHEMBL15599403 | 0.85 | MCL1 (0.42) | BCL2L1MCL1RAB9ANPC1MAPT | |
| SCHEMBL15599413 | 0.81 | MCL1 (0.40) | BCL2L1MCL1RAB9ANPC1MAPT | |
| SCHEMBL14680638 | 0.81 | ESR1 (0.41) | BCL2L1MCL1RAB9AMAPTLMNA | |
| SCHEMBL812518 | 0.80 | BCL2L1 (0.50) | BCL2L1MCL1RAB9ANPC1MAPT | |
| SCHEMBL14295769 | 0.80 | LIMK1 (0.44) | BCL2L1MCL1RAB9ANPC1MAPT | |
| SCHEMBL20156869 | 0.80 | MAPT (0.41) | BCL2L1MCL1RAB9ANPC1MAPT | |
| SCHEMBL10133864 | 0.79 | BCL2L1 (0.38) | BCL2L1MCL1RAB9ANPC1MAPT | |
| SCHEMBL10133866 | 0.79 | BCL2L1 (0.41) | BCL2L1MCL1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230320191-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-10-05 | — | — | US | disclosed |
| US-11659763-B2 | Metal complexes | MERCK PATENT GMBH | 2023-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230320191-A1 | METAL COMPLEXES | IMMT, MCU, SOD1 | BCL2L1 2366/4885MCL1 2794/4885RAB9A 2000/4885 |
| US-11659763-B2 | Metal complexes | IMMT, MCU, SOD1 | BCL2L1 2366/4885MCL1 2794/4885RAB9A 2000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.