Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | MITF | O75030 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2552921 | 0.98 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MITFRAB9APAX8 | |
| SCHEMBL30771327 | 0.88 | GAA (0.57) | ALDH1A1SMN1; SMN2MITFRAB9APAX8 | |
| SCHEMBL10502713 | 0.87 | GAA (0.52) | ALDH1A1SMN1; SMN2MITFRAB9APAX8 | |
| SCHEMBL2551775 | 0.87 | SMN1; SMN2 (0.65) | ALDH1A1SMN1; SMN2MITFPAX8HTT | |
| SCHEMBL1683001 | 0.85 | LMNA (0.64) | ALDH1A1SMN1; SMN2MITFRAB9APAX8 | |
| SCHEMBL17616735 | 0.83 | MITF (0.68) | ALDH1A1SMN1; SMN2MITFRAB9APAX8 | |
| SCHEMBL4207828 | 0.83 | KDM4E (0.49) | ALDH1A1SMN1; SMN2MITFRAB9APAX8 | |
| SCHEMBL21807155 | 0.82 | GAA (0.50) | ALDH1A1SMN1; SMN2MITFRAB9APAX8 | |
| SCHEMBL7592795 | 0.82 | MITF (0.71) | ALDH1A1SMN1; SMN2MITFRAB9APAX8 | |
| SCHEMBL12282101 | 0.82 | MITF (0.71) | ALDH1A1SMN1; SMN2MITFRAB9APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10457693-B2 | Organoboron compounds and methods of making organoboron compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-10-29 | — | — | US | disclosed |
| US-20190031688-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-01-31 | — | — | US | disclosed |
| US-9512147-B2 | Organoboron compounds and methods of making organoboron compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-12-06 | — | — | US | disclosed |
| US-20160083402-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-03-24 | — | — | US | disclosed |
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083402-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | NDC1, ELOC, UGT2B7 | ALDH1A1 1921/4885SMN1; SMN2 1952/4885MITF 3166/4885 |
| US-10457693-B2 | Organoboron compounds and methods of making organoboron compounds | NDC1, ELOC, UGT2B7 | ALDH1A1 1921/4885SMN1; SMN2 1952/4885MITF 3166/4885 |
| US-20190031688-A1 | ORGANOBORON COMPOUNDS AND METHODS OF MAKING ORGANOBORON COMPOUNDS | NDC1, ELOC, UGT2B7 | ALDH1A1 1921/4885SMN1; SMN2 1952/4885MITF 3166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.