SCHEMBL25523675

SCHEMBL25523675

CC(C)(C)c1ccc(-n2c3ccccc3c3c(CC(C)(C)c4ccncc4)cccc32)nc1

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MKNK1 Q9BUB5 2/20 0.32
MKNK2 Q9HBH9 1/20 0.32
CYP19A1 P11511 1/20 0.31
TRPV1 Q8NER1 1/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.31
PDGFRB P09619 1/20 0.31
KIT P10721 1/20 0.31
FLT1 P17948 1/20 0.31
KDR P35968 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
TOP2A P11388 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25028416 0.83 ALDH1A1 (0.33) TRPV1
SCHEMBL24848467 0.82 MKNK1 (0.35) MKNK1MKNK2TRPV1PTGDR2PDGFRB
SCHEMBL23011291 0.77 KDM4E (0.37)
SCHEMBL21453891 0.77 MKNK1 (0.35) MKNK1MKNK2TRPV1PTGDR2KDR
SCHEMBL21453895 0.77 MAOA (0.43) MKNK1MKNK2TRPV1PTGDR2KDR
SCHEMBL25718645 0.75 MGLL (0.30)
SCHEMBL25028796 0.68 MEN1 (0.32)
SCHEMBL24848703 0.68 MKNK1 (0.32) MKNK1MKNK2
SCHEMBL21453890 0.67 UQCRB (0.37)
SCHEMBL18531564 0.67 KIF11 (0.43) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159578-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159578-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, DRD3 MKNK1 4807/4885MKNK2 4790/4885CYP19A1 394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.