Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.50 |
| ▸ | THRA | P10827 | 10/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23003693 | 0.91 | THRB (0.59) | THRBTHRAPTGS1PTGS2LTA4H | |
| SCHEMBL23003657 | 0.88 | THRB (0.47) | THRBTHRATRPM8 | |
| SCHEMBL25528657 | 0.86 | THRA (0.55) | THRBTHRAHSP90AA1 | |
| SCHEMBL25528658 | 0.85 | THRB (0.54) | THRBTHRAHSP90AA1 | |
| SCHEMBL25528726 | 0.85 | THRA (0.56) | THRBTHRAHSP90AA1 | |
| SCHEMBL25528579 | 0.84 | THRA (0.51) | THRBTHRA | |
| SCHEMBL25528612 | 0.84 | THRA (0.53) | THRBTHRAHSP90AA1HSP90B1 | |
| SCHEMBL25528646 | 0.83 | THRA (0.52) | THRBTHRA | |
| SCHEMBL25528690 | 0.82 | THRB (0.49) | THRBTHRAPTGS1PTGS2LTA4H | |
| SCHEMBL25528661 | 0.82 | THRB (0.51) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667606-B2 | Thyromimetics | AUTOBAHN THERAPEUTICS, INC. (US) | 2023-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667606-B2 | Thyromimetics | TPO, TSHR, TTR | THRB 9/4885THRA 4/4885PTGS1 514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.