Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.49 |
| ▸ | THRA | P10827 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23003742 | 0.91 | THRB (0.58) | THRBTHRALMNATP53POLB | |
| SCHEMBL23003800 | 0.88 | THRB (0.46) | THRBTHRALMNATP53POLB | |
| SCHEMBL25528726 | 0.84 | THRA (0.56) | THRBTHRAHPGD | |
| SCHEMBL25528657 | 0.83 | THRA (0.55) | THRBTHRALMNAALDH1A1HPGD | |
| SCHEMBL25528569 | 0.82 | THRB (0.50) | THRBTHRALMNATP53POLB | |
| SCHEMBL25528689 | 0.82 | THRB (0.50) | THRBTHRATRPM8PTGS1PTGS2 | |
| SCHEMBL25528646 | 0.82 | THRA (0.52) | THRBTHRALMNAPOLBALDH1A1 | |
| SCHEMBL25528658 | 0.82 | THRB (0.54) | THRBTHRAHPGD | |
| SCHEMBL25528612 | 0.81 | THRA (0.53) | THRBTHRALMNAALDH1A1GAA | |
| SCHEMBL25528655 | 0.80 | THRA (0.50) | THRBTHRAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667606-B2 | Thyromimetics | AUTOBAHN THERAPEUTICS, INC. (US) | 2023-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667606-B2 | Thyromimetics | TPO, TSHR, TTR | THRB 9/4885THRA 4/4885LMNA 1391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.