Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131403 | 0.86 | RAPGEF4 (0.54) | ALDH1A1TSHRCYP2C9CYP2C19RAPGEF4 | |
| SCHEMBL10695412 | 0.85 | ALDH1A1 (0.59) | ALDH1A1TSHRPTGS2CYP2C9CYP2C19 | |
| SCHEMBL7341065 | 0.84 | LMNA (0.54) | ALDH1A1TSHRPTGS2CYP2C9CYP2C19 | |
| SCHEMBL1921293 | 0.80 | RAPGEF4 (0.57) | ALDH1A1TSHRPTGS2RAPGEF4MEN1 | |
| SCHEMBL4333864 | 0.80 | LMNA (0.60) | ALDH1A1TSHRCYP2C9CYP2C19TDP1 | |
| SCHEMBL14306858 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRPTGS2CYP2C9CYP2C19 | |
| SCHEMBL31333015 | 0.78 | CXCL8 (0.49) | ALDH1A1TSHRPTGS2CYP2C9CYP2C19 | |
| SCHEMBL2553022 | 0.78 | CXCL8 (0.49) | ALDH1A1TSHRPTGS2CYP2C9CYP2C19 | |
| SCHEMBL4800221 | 0.78 | RAPGEF4 (0.55) | ALDH1A1PTGS2RAPGEF4TDP1MEN1 | |
| SCHEMBL6131394 | 0.77 | LMNA (0.41) | ALDH1A1TSHRCYP2C9CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010044511-A1 | Polymerization of olefins | E.I. DU PONT DE NEMOURS AND COMPANY | 2001-11-22 | — | — | US | disclosed |
| WO-2001072854-A2 | POLYMERIZATION OF OLEFINS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2001-10-04 | — | — | WO | disclosed |