Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 2/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CD74 | P04233 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25529500 | 0.90 | ROCK2 (0.59) | ROCK1ROCK2TNIKIDO1GAA | |
| SCHEMBL25530881 | 0.86 | ROCK2 (0.48) | ROCK1ROCK2TNIKIDO1GAA | |
| SCHEMBL25529498 | 0.82 | MAPT (0.48) | ROCK1ROCK2TNIKIDO1GAA | |
| SCHEMBL25530887 | 0.81 | KMT2A (0.39) | ROCK1ROCK2IDO1KMT2A | |
| SCHEMBL25530633 | 0.81 | ROCK2 (0.45) | ROCK1ROCK2TNIKIDO1GAA | |
| SCHEMBL25529501 | 0.80 | ROCK1 (0.47) | ROCK1ROCK2IDO1KMT2A | |
| SCHEMBL25528328 | 0.79 | BRD4 (0.43) | ROCK1ROCK2CYP3A4 | |
| SCHEMBL25528181 | 0.76 | ROCK2 (0.59) | ROCK1ROCK2TNIKCYP3A4PRKACA | |
| SCHEMBL25528180 | 0.76 | ROCK2 (0.59) | ROCK1ROCK2TNIKCYP3A4PRKACA | |
| SCHEMBL25528176 | 0.76 | ROCK2 (0.57) | ROCK1ROCK2TNIKCYP3A4PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093787-A1 | BENZODIAZEPINE COMPOUND AND APPLICATION THEREOF AS RHO KINASE INHIBITOR | 成都奥睿药业有限公司 | 2023-06-01 | — | — | WO | disclosed |