Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203374 | 0.96 | CTSL (0.51) | LMNASMN1; SMN2KDM4ECTSLCTSB | |
| SCHEMBL25532256 | 0.89 | LMNA (0.47) | LMNASMN1; SMN2CTSLCTSBCTSS | |
| SCHEMBL7841236 | 0.87 | MEN1 (0.53) | LMNAKDM4EL3MBTL1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL22233162 | 0.83 | MEN1 (0.44) | LMNASMN1; SMN2KDM4ECTSLCTSB | |
| SCHEMBL4870701 | 0.82 | LMNA (0.54) | LMNASMN1; SMN2CTSLCTSBCTSS | |
| SCHEMBL6187228 | 0.81 | ITGB3 (0.51) | LMNASMN1; SMN2KDM4EL3MBTL1NPC1 | |
| SCHEMBL6191239 | 0.81 | MEN1 (0.48) | LMNANPC1RAB9AMEN1KMT2A | |
| SCHEMBL4861409 | 0.81 | CTSL (0.53) | LMNASMN1; SMN2CTSLCTSBCTSS | |
| SCHEMBL3647693 | 0.81 | CTSL (0.53) | LMNASMN1; SMN2CTSLCTSBCTSS | |
| SCHEMBL10332172 | 0.81 | CTSS (0.59) | LMNASMN1; SMN2KDM4ECTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | LMNA 3813/4885SMN1; SMN2 4817/4885KDM4E 3027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.