SCHEMBL2553985

SCHEMBL2553985

CCON(O)c1ccc(N)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.48
CYP3A4 P08684 6/20 0.48
ALDH1A1 P00352 4/20 0.48
TSHR P16473 4/20 0.48
MAPK1 P28482 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
PSMD14 O00487 1/20 0.48
RECQL P46063 1/20 0.48
GFER P55789 1/20 0.48
TP53 P04637 2/20 0.43
ALOX15 P16050 1/20 0.43
CYP1A2 P05177 3/20 0.41
MAOA P21397 2/20 0.41
LMNA P02545 2/20 0.41
MAPT P10636 3/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP19A1 P11511 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27571352 0.78 TDP1 (0.52) TDP1CYP3A4ALDH1A1TSHRMAPK1
SCHEMBL1979093 0.77 CYP3A4 (0.50) TDP1CYP3A4ALDH1A1TSHRMAPK1
SCHEMBL6816251 0.75 TDP1 (0.54) TDP1CYP3A4ALDH1A1TSHRMAPK1
SCHEMBL10442224 0.73 TDP1 (0.47) TDP1CYP3A4ALDH1A1TSHRMAPK1
Sulfuric Acid SCHEMBL28070216 0.73 ALDH1A1 (0.42) TDP1CYP3A4ALDH1A1TSHRMAPK1
SCHEMBL27496182 0.73 CYP3A4 (0.42) TDP1CYP3A4ALDH1A1TSHRMAPK1
SCHEMBL27885808 0.72 TDP1 (0.41) TDP1CYP3A4ALDH1A1TSHRMAPK1
SCHEMBL459307 0.71 ALDH1A1 (0.60) TDP1CYP3A4ALDH1A1TSHRMAPK1
SCHEMBL27462576 0.71 TDP1 (0.40) TDP1CYP3A4ALDH1A1TSHRMAPK1
SCHEMBL457545 0.70 CYP3A4 (0.41) TDP1CYP3A4ALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3464247-A1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES L'Oréal (FR) 2019-04-10 EP claimed
WO-2017202884-A1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES L'OREAL (FR) 2017-11-30 WO claimed
US-6692537-B1 ENZYME OF 2-ELECTRON OXIDOREDUCTASE TYPE IN THE PRESENCE OF AT LEAST ONE DONOR FOR THE SAID ENZYME AND AT LEAST ONE NONIONIC FATTY SUCRONAMIDE L'OREAL S.A. (FR) 2004-02-17 US claimed
WO-2025069042-A1 COMPOSITIONS AND METHODS FOR DYEING AND/OR LIGHTENING KERATIN FIBRES L'OREAL (FR) 2025-04-03 WO disclosed
EP-4395734-A1 COMPOSITIONS, KITS, AND METHODS FOR ALTERING THE COLOR OF HAIR L'OREAL (FR) 2024-07-10 EP disclosed
WO-2024134667-A1 A DEVICE COMPRISING OXIDATIVE COMPOSITION FOR DYEING OF KERATIN FIBRES L'OREAL (FR) 2024-06-27 WO disclosed
EP-4362891-A1 COMPOSITION COMPRISING AT LEAST ONE PARTICULAR COUPLER, AT LEAST ONE PARTICULAR OXIDATION BASE, AT LEAST ONE FATTY SUBSTANCE AND AT LEAST ONE ANIONIC POLYSACCHARIDE L'OREAL (FR) 2024-05-08 EP disclosed
EP-4362890-A1 COMPOSITION COMPRISING AT LEAST ONE OXIDATION DYE, AT LEAST ONE ALKALINE AGENT AND AT LEAST ONE LIQUID FATTY ALCOHOL AND AT LEAST ONE SOLID FATTY ALCOHOL L'OREAL (FR) 2024-05-08 EP disclosed
US-20240074960-A1 COSMETIC COMPOSITION COMPRISING A COMBINATION OF TWO PARTICULAR COUPLERS AND N,N-DICARBOXYMETHYLGLUTAMIC ACID AND/OR ITS SALTS L'OREAL (FR) 2024-03-07 US disclosed
WO-2024026212-A1 HAIR COLORING WITH COCONUT OIL L'OREAL (FR) 2024-02-01 WO disclosed
EP-4262695-A1 COSMETIC COMPOSITION COMPRISING A COMBINATION OF TWO PARTICULAR COUPLERS AND A NONIONIC SURFACTANT OF ALKYLPOLYGLYCOSIDE TYPE L'OREAL (FR) 2023-10-25 EP disclosed
WO-2012076536-A1 OXIDATION DYE COMPOSITION COMPRISING A POLYCONDENSATE OF ETHYLENE OXIDE AND OF PROPYLENE OXIDE, AND AN UNSATURATED FATTY ALCOHOL L'OREAL (FR) 2012-06-14 WO disclosed
WO-2012059405-A1 MOUSSE DYE COMPOSITION COMPRISING AN ASSOCIATIVE POLYMER L'OREAL (FR) 2012-05-10 WO disclosed
WO-2012059407-A1 FOAM DYE COMPOSITION COMPRISING A MONOSACCHARIDE OR DISACCHARIDE L'OREAL (FR) 2012-05-10 WO disclosed
WO-2012059408-A1 FOAM DYE COMPOSITION COMPRISING AT LEAST ONE PARTICULAR POLYOXYETHYLENATED FATTY ALCOHOL L'OREAL (FR) 2012-05-10 WO disclosed
WO-2011138838-A1 READY-TO-USE COSMETIC COMPOSITION FOR OXIDATION DYEING KERATIN FIBERS L'OREAL (FR) 2011-11-10 WO disclosed
WO-2011121008-A1 HAIR TREATMENT PROCESS USING A DIRECT EMULSION COMPRISING AN OXIDIZING AGENT AND A DIRECT EMULSION CONTAINING AN ALKALINE AGENT L'OREAL (FR) 2011-10-06 WO disclosed
WO-2010133640-A2 DYEING COMPOSITION COMPRISING A SECONDARY PARA-PHENYLENEDIAMINE OXIDATION BASE AND A HETEROCYCLIC OXIDATION BASE L'OREAL (FR) 2010-11-25 WO disclosed
WO-2005014591-A1 2-ACYLAMINO OR 2-SULFONYLAMINO-1, 3-THIAZOLES AS COUPLERS FOR THE OXIDATION DYEING OF KERATIN FIBRES L'OREAL (FR) 2005-02-17 WO disclosed
US-20030172473-A1 Composition useful for the oxidation dyeing of keratin fibres, containing an oxyalkylenated carboxylic acid ether, a nonionic surfactant and a particular polymer L'OREAL (FR) 2003-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074960-A1 COSMETIC COMPOSITION COMPRISING A COMBINATION OF TWO PARTICULAR COUPLERS AND N,N-DICARBOXYMETHYLGLUTAMIC ACID AND/OR ITS SALTS SDHA, SDHB, GRHPR TDP1 2557/4885CYP3A4 969/4885ALDH1A1 950/4885
US-20030172473-A1 Composition useful for the oxidation dyeing of keratin fibres, containing an oxyalkylenated carboxylic acid ether, a nonionic surfactant and a particular polymer KRT18, KRTCAP2, CUTA TDP1 3533/4885CYP3A4 2088/4885ALDH1A1 1206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.