Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6195039 | 0.85 | MAPT (0.59) | NPC1RAB9APIK3CAMAPTMEN1 | |
| SCHEMBL7029291 | 0.78 | PIK3CA (0.70) | NPC1RAB9APIK3CAMAPTMEN1 | |
| SCHEMBL1404500 | 0.77 | MAPK1 (0.65) | NPC1RAB9AESR1SHBGESR2 | |
| SCHEMBL29514772 | 0.77 | ESR1 (0.81) | NPC1RAB9AESR1SHBGESR2 | |
| SCHEMBL3586687 | 0.77 | ESR1 (0.81) | NPC1RAB9AESR1SHBGESR2 | |
| SCHEMBL3956227 | 0.77 | ESR1 (0.65) | NPC1RAB9AESR1SHBGESR2 | |
| SCHEMBL5725840 | 0.75 | RAB9A (1.00) | NPC1RAB9AESR1SHBGESR2 | |
| SCHEMBL10649146 | 0.75 | RAB9A (1.00) | NPC1RAB9AESR1SHBGESR2 | |
| SCHEMBL4449153 | 0.74 | ERCC5 (0.62) | RAB9AMAPTMEN1CYP3A4HPGD | |
| SCHEMBL9526213 | 0.74 | ALDH1A1 (0.71) | MAPTMEN1CYP3A4HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159549-A1 | METHOD FOR PREPARATION OF ASENAPINE | ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159549-A1 | METHOD FOR PREPARATION OF ASENAPINE | CYP3A5, QDPR, SPR | NPC1 523/4885RAB9A 1014/4885ESR1 4591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.