Terephthalamide

Terephthalamide

SCHEMBL2554096

CC1CCCCC1(C)C(N)(N)C1CCCCC1.NC(=O)c1ccc(C(N)=O)cc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 4/20 0.42
PARP10 Q53GL7 4/20 0.39
PARP15 Q460N3 3/20 0.39
OPRD1 P41143 3/20 0.37
PDE4D Q08499 2/20 0.36
PDE7A Q13946 1/20 0.36
CYP2C9 P11712 1/20 0.35
OPRK1 P41145 2/20 0.34
PDE4A P27815 1/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34
PARP2 Q9UGN5 1/20 0.34
NPC1 O15118 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
CYP1A2 P05177 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalamide SCHEMBL900384 0.85 OPRM1 (0.44) OPRM1PARP10PARP15OPRD1PDE4D
SCHEMBL223336 0.84 ALDH1A1 (0.31) ALDH1A1
Isophthalic Acid SCHEMBL17802593 0.84 KMO (0.43) OPRM1OPRD1PDE4DPDE7AOPRK1
SCHEMBL15412728 0.75 NAAA (0.39) KDM4ECYP1A2CYP2C19
Terephthalamide SCHEMBL5509609 0.70 PARP10 (0.53) PARP10PARP15PDE4DPDE7ACYP2C9
Terephthalamide SCHEMBL12613686 0.66 PARP1 (0.60) PARP10PARP15PARP2ALDH1A1MAPT
Terephthalamide SCHEMBL197479 0.66 PARP1 (0.60) PARP10PARP15PARP2ALDH1A1MAPT
SCHEMBL2907552 0.66
SCHEMBL1160170 0.66 GAA (0.50) OPRM1PARP10PARP15ALDH1A1LMNA
Terephthalamide SCHEMBL472214 0.66 PARP1 (0.60) PARP10PARP15PARP2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2638110-B1 HALOGEN-FREE FLAME RETARDANT POLYAMIDE COMPOSITION DU PONT (US) 2019-06-12 EP disclosed
EP-2872559-A1 FLAME-RETARDANT POLYMER COMPOSITIONS AND MOLDED ARTICLES COMPRISING THE SAME E. I. du Pont de Nemours and Company (US) 2015-05-20 EP disclosed
WO-2014011515-A1 FLAME-RETARDANT POLYMER COMPOSITIONS AND MOLDED ARTICLES COMPRISING THE SAME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-01-16 WO disclosed
EP-2553020-A2 FLAME RESISTANT POLYAMIDE RESIN COMPOSITION AND ARTICLES COMRPISING THE SAME E.I. Du Pont De Nemours And Company (US) 2013-02-06 EP disclosed
WO-2012088207-A2 MOLDED THERMOPLASTIC ARTICLES COMPRISING THERMALLY CONDUCTIVE POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-28 WO disclosed
WO-2011126794-A2 FLAME RESISTANT POLYAMIDE RESIN COMPOSITION AND ARTICLES COMRPISING THE SAME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-10-13 WO disclosed