Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DCK | P27707 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25556504 | 0.88 | ALDH1A1 (0.37) | ALDH1A1LMNAKMT2AGRM2KDM4E | |
| SCHEMBL25545936 | 0.88 | PAX8 (0.39) | ALDH1A1LMNAKMT2AGRM2KDM4E | |
| SCHEMBL25180286 | 0.88 | GRM2 (0.41) | ALDH1A1LMNAKMT2AGRM2KDM4E | |
| SCHEMBL25546218 | 0.88 | GRM2 (0.43) | ALDH1A1GRM2 | |
| SCHEMBL25546019 | 0.84 | FBP1 (0.41) | ALDH1A1LMNAKMT2AGRM2KDM4E | |
| SCHEMBL25556506 | 0.83 | XDH (0.38) | ALDH1A1LMNAKMT2AKDM4EMAPT | |
| SCHEMBL25545980 | 0.79 | ALDH1A1 (0.36) | ALDH1A1KDM4EHTT | |
| SCHEMBL25545940 | 0.79 | NOTUM (0.44) | ALDH1A1KMT2AKDM4EFGFR2NPC1 | |
| SCHEMBL25556500 | 0.79 | LMNA (0.38) | ALDH1A1LMNAKMT2AGRM2KDM4E | |
| SCHEMBL25546067 | 0.78 | RIPK2 (0.41) | ALDH1A1LMNAGRM2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150997-A1 | EIF4E INHIBITORS AND USES THEREOF | EIF4E, EIF4EBP1, EIF4A1 | ALDH1A1 4776/4885LMNA 2647/4885KMT2A 1931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.