Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23241569 | 0.86 | RXRA (0.49) | KLKB1KDM4ESMN1; SMN2NPSR1RXRA | |
| SCHEMBL4844663 | 0.81 | ALDH1A1 (0.46) | KLKB1KDM4ESMN1; SMN2LOXL2 | |
| SCHEMBL18656545 | 0.79 | CSNK2A1 (0.46) | KLKB1LOXL2NOS1NOS2NOS3 | |
| SCHEMBL8141320 | 0.78 | HRH3 (0.40) | KLKB1LOXL2 | |
| SCHEMBL4050941 | 0.77 | NPC1 (0.45) | SMN1; SMN2CYP3A4NPSR1 | |
| SCHEMBL27263781 | 0.77 | SHBG (0.42) | KLKB1LOXL2NOS1NOS2NOS3 | |
| SCHEMBL9715576 | 0.77 | BCHE (0.43) | NPSR1 | |
| SCHEMBL28148703 | 0.76 | CFD (0.44) | KDM4ESMN1; SMN2LOXL2CYP3A4 | |
| SCHEMBL28346847 | 0.76 | HSD17B1 (0.47) | KDM4ECYP3A4NPSR1RXRARXRB | |
| SCHEMBL28192545 | 0.75 | KDM4E (0.47) | KLKB1KDM4ERXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023099669-A1 | PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR | ZEALAND PHARMA A/S (DK) | 2023-06-08 | — | — | WO | disclosed |