Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 9/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 9/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13304198 | 0.90 | LMNA (0.40) | CYP2D6LMNAPDK2AKR1C3AKR1C2 | |
| SCHEMBL19879077 | 0.80 | PDE2A (0.39) | CYP2D6AKR1C3AKR1C2HIF1ACYP2C9 | |
| SCHEMBL10030654 | 0.79 | GLA (0.48) | LMNAPDK2AKR1C3AKR1C2GAA | |
| SCHEMBL10624896 | 0.78 | NOTUM (0.44) | CYP2D6LMNAPDK2AKR1C3AKR1C2 | |
| SCHEMBL1104680 | 0.78 | SLC6A4 (0.42) | LMNAPDK2AKR1C3AKR1C2TRPA1 | |
| SCHEMBL12868131 | 0.78 | LMNA (0.47) | CYP2D6LMNAPDK2AKR1C3AKR1C2 | |
| SCHEMBL1109056 | 0.78 | LMNA (0.52) | LMNAPDK2AKR1C3AKR1C2TRPA1 | |
| SCHEMBL10267400 | 0.78 | LMNA (0.38) | CYP2D6CYP1A2LMNAPDK2AKR1C3 | |
| SCHEMBL17123654 | 0.78 | CYP2D6 (0.38) | CYP2D6CYP1A2LMNAPDK2AKR1C3 | |
| SCHEMBL8146090 | 0.78 | KIF11 (0.48) | AKR1C3AKR1C2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210853-A1 | TARGETED NEK7 INHIBITION FOR MODULATION OF THE NLRP3 INFLAMMASOME | Halia Therapeutics, Inc. | 2023-07-06 | — | — | US | disclosed |
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | CYP2D6 1521/4885CYP1A2 3539/4885LMNA 3813/4885 |
| US-20230210853-A1 | TARGETED NEK7 INHIBITION FOR MODULATION OF THE NLRP3 INFLAMMASOME | NEK7, NLRP3, NOD1 | CYP2D6 4762/4885CYP1A2 4720/4885LMNA 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.