Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25568288 | 0.86 | LMNA (0.51) | SMN1; SMN2LMNAHTTALDH1A1MEN1 | |
| SCHEMBL4862689 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAHTTALDH1A1FUCA1 | |
| SCHEMBL30772669 | 0.80 | ALDH1A1 (0.50) | SMN1; SMN2LMNAHTTALDH1A1CTSL | |
| SCHEMBL6535838 | 0.78 | HTT (0.52) | SMN1; SMN2LMNAHTTALDH1A1CTSL | |
| SCHEMBL6240346 | 0.77 | ALDH1A1 (0.48) | SMN1; SMN2LMNAHTTALDH1A1FUCA1 | |
| SCHEMBL4870656 | 0.77 | ALDH1A1 (0.48) | SMN1; SMN2LMNAHTTALDH1A1FUCA1 | |
| Hydrochloric Acid SCHEMBL30117949 | 0.77 | HTT (0.51) | SMN1; SMN2LMNAHTTALDH1A1CTSL | |
| SCHEMBL31268160 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KMT2AL3MBTL1HTR2CTSHR | |
| SCHEMBL25568218 | 0.76 | ALDH1A1 (0.47) | SMN1; SMN2LMNAHTTALDH1A1FUCA1 | |
| SCHEMBL25568219 | 0.76 | ALDH1A1 (0.47) | SMN1; SMN2LMNAHTTALDH1A1FUCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159517-A1 | CHROMANE AMIDINE MONOBACTAM COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | MERCK SHARP & DOHME LLC (US) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159517-A1 | CHROMANE AMIDINE MONOBACTAM COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | TCOF1, SLC10A2, PAM | SMN1; SMN2 1717/4885LMNA 1047/4885HTT 3703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.