Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PPID | Q08752 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL25582 | 0.86 | LMNA (0.36) | CTSLCTSBLMNAALDH1A1PPID | |
| SCHEMBL560784 | 0.84 | CTSS (0.36) | SLC15A1CTSSCTSLCTSBLMNA | |
| SCHEMBL5145725 | 0.84 | — | — | |
| SCHEMBL5148801 | 0.80 | SLC15A1 (0.42) | SLC15A1CTSSCTSLCTSBALDH1A1 | |
| SCHEMBL27612210 | 0.77 | LTA4H (0.43) | SLC15A1CTSSCTSLCTSBALDH1A1 | |
| Acetic Acid SCHEMBL560785 | 0.75 | LMNA (0.40) | CTSSCTSLCTSBLMNAALDH1A1 | |
| SCHEMBL10408165 | 0.74 | ALDH1A1 (0.45) | SLC15A1CTSSCTSLCTSBLMNA | |
| SCHEMBL27622479 | 0.73 | CYP2D6 (0.40) | LMNAALDH1A1 | |
| SCHEMBL6368352 | 0.73 | ALDH1A1 (0.42) | SLC15A1CTSSCTSLCTSBLMNA | |
| SCHEMBL6368367 | 0.73 | ALDH1A1 (0.49) | SLC15A1CTSSCTSLCTSBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902714-B1 | Prodrugs of gaba analogs, compositions and uses thereof | XENOPORT INC (US) | 2012-01-11 | — | — | EP | disclosed |
| EP-2085087-A1 | Prodrugs of gaba analogs, compositions and uses thereof | Xenoport, Inc. (US) | 2009-08-05 | — | — | EP | disclosed |
| EP-1902714-A1 | Prodrugs of gaba analogs, compositions and uses thereof | Xenoport, Inc. (US) | 2008-03-26 | — | — | EP | disclosed |