Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368367 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL27612210 | 0.83 | LTA4H (0.43) | ALDH1A1KMT2AMAPK1L3MBTL1SLC15A1 | |
| SCHEMBL6368413 | 0.81 | TSHR (0.41) | ALDH1A1KMT2ATDP1MEN1CYP1A2 | |
| SCHEMBL5148801 | 0.80 | SLC15A1 (0.42) | ALDH1A1KMT2AMAPK1L3MBTL1SLC15A1 | |
| SCHEMBL10408165 | 0.79 | ALDH1A1 (0.45) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL10408344 | 0.77 | CTSL (0.46) | ALDH1A1KMT2AMAPK1L3MBTL1SLC15A1 | |
| SCHEMBL7509351 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL27534954 | 0.74 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL14148977 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| Hydrochloric Acid SCHEMBL3699844 | 0.73 | ALDH1A1 (0.51) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050059735-A1 | Cyclic amino acid derivatives useful as pharmaceutical agents | BRYANS JUSTIN STEPHEN (GB) | 2005-03-17 | — | — | US | claimed |
| US-20030216469-A1 | Cyclic amino acid derivatives useful as pharmaceutical agents | BRYANS JUSTIN STEPHEN (GB) | 2003-11-20 | — | — | US | claimed |
| US-20050059735-A1 | Cyclic amino acid derivatives useful as pharmaceutical agents | BRYANS JUSTIN STEPHEN (GB) | 2005-03-17 | — | — | US | disclosed |
| US-20030216469-A1 | Cyclic amino acid derivatives useful as pharmaceutical agents | BRYANS JUSTIN STEPHEN (GB) | 2003-11-20 | — | — | US | disclosed |
| EP-1284960-A1 | CYCLIC AMINO ACID DERIVATIVES USEFUL AS PHARMACEUTICAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001090052-A1 | CYCLIC AMINO ACID DERIVATIVES USEFUL AS PHARMACEUTICAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059735-A1 | Cyclic amino acid derivatives useful as pharmaceutical agents | QPCT, ARGLU1, PNISR | ALDH1A1 3285/4885KMT2A 3098/4885MAPK1 1366/4885 |
| US-20030216469-A1 | Cyclic amino acid derivatives useful as pharmaceutical agents | QPCT, ARGLU1, QPCTL | ALDH1A1 3091/4885KMT2A 3288/4885MAPK1 1038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.