Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
| ▸ | TLR2 | O60603 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12055210 | 0.87 | KDM4E (0.48) | FOLH1SMN1; SMN2EPHX1SIRT5SIRT6 | |
| SCHEMBL16231519 | 0.87 | KDM4E (0.48) | FOLH1SMN1; SMN2EPHX1SIRT5SIRT6 | |
| SCHEMBL22800728 | 0.85 | SIRT6 (0.35) | FOLH1SMN1; SMN2EPHX1SIRT5SIRT6 | |
| SCHEMBL763069 | 0.84 | MEN1 (0.53) | FOLH1SMN1; SMN2EPHX1SIRT6SIRT1 | |
| SCHEMBL21913856 | 0.84 | ALDH1A1 (0.43) | FOLH1KMT2AMEN1 | |
| SCHEMBL22570776 | 0.83 | ACHE (0.39) | EPHX1 | |
| SCHEMBL16231545 | 0.83 | FOLH1 (0.42) | FOLH1SIRT5 | |
| SCHEMBL21297374 | 0.83 | KISS1R (0.39) | EPHX1 | |
| SCHEMBL16248631 | 0.83 | KDM4E (0.35) | KDM4E | |
| SCHEMBL21891783 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023096904-A2 | C-16 MODIFIED TRIOXACARCINS, ANTIBODY DRUG CONJUGATES, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-06-01 | — | — | WO | disclosed |