Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25599242 | 0.87 | ALDH1A1 (0.40) | LMNAHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL25599429 | 0.85 | HSD11B1 (0.38) | LMNAHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL25221933 | 0.81 | GAA (0.34) | LMNAHPGDALDH1A1KCNH2MAPT | |
| SCHEMBL30533956 | 0.81 | GAA (0.34) | LMNAHPGDALDH1A1KCNH2MAPT | |
| SCHEMBL25599094 | 0.81 | ALDH1A1 (0.52) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL25220875 | 0.78 | CHRM4 (0.34) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL25599264 | 0.76 | KCNH2 (0.44) | LMNAALDH1A1MEN1KMT2AKCNH2 | |
| SCHEMBL25599685 | 0.76 | KCNH2 (0.37) | LMNAALDH1A1MEN1KMT2AKCNH2 | |
| SCHEMBL25258895 | 0.75 | KCNH2 (0.40) | ALDH1A1MEN1KMT2AKCNH2MAPT | |
| SCHEMBL25258893 | 0.75 | KCNH2 (0.40) | ALDH1A1MEN1KMT2AKCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102184-A1 | BICYCLIC AMINE COMPOUNDS AS CDK12 INHIBITORS | INCYTE CORPORATION (US) | 2023-06-08 | — | — | WO | disclosed |