Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 12/20 | 0.40 |
| ▸ | CCNK | O75909 | 2/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25599771 | 0.93 | CCNA2 (0.37) | BTKCCNKCDK12EGFR | |
| SCHEMBL25599780 | 0.88 | IRAK4 (0.41) | CCNKCDK12EGFRADORA2AADORA1 | |
| SCHEMBL25599216 | 0.84 | CCNA2 (0.39) | BTKCCNKCDK12KDM4E | |
| SCHEMBL25682533 | 0.84 | CCNA2 (0.39) | BTKCCNKCDK12KDM4E | |
| SCHEMBL25599817 | 0.84 | UCHL3 (0.37) | CCNKCDK12EGFR | |
| SCHEMBL25599631 | 0.84 | CDK7 (0.38) | BTKCCNKCDK12EGFR | |
| SCHEMBL25681855 | 0.83 | BRPF1 (0.39) | EGFR | |
| SCHEMBL25599672 | 0.83 | CCNA2 (0.38) | CCNKCDK12EGFR | |
| SCHEMBL25599717 | 0.83 | BRPF1 (0.39) | EGFR | |
| SCHEMBL25599189 | 0.83 | UCHL3 (0.36) | CCNKCDK12EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102184-A1 | BICYCLIC AMINE COMPOUNDS AS CDK12 INHIBITORS | INCYTE CORPORATION (US) | 2023-06-08 | — | — | WO | disclosed |