SCHEMBL25607236

SCHEMBL25607236

CC(C)(C)OC(=O)CC[C@H](NC(=O)C(C)(C)NC(=O)[C@H](Cc1ccc(OC(C)(C)C)cc1)NC(=O)OC(C)(C)C)C(=O)NCC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ ABCB1 P08183 1/20 0.47
▸ CTSS P25774 12/20 0.46
▸ CTSK P43235 11/20 0.46
▸ CTSB P07858 4/20 0.46
▸ CTSL P07711 2/20 0.46
▸ HDAC8 Q9BY41 1/20 0.42
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ AKT1 P31749 1/20 0.41
▸ ITGB3 P05106 1/20 0.41
▸ ITGA2B P08514 1/20 0.41
▸ BCL2 P10415 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25607238 0.94 ABCB1 (0.46) ABCB1CTSSCTSKCTSBCTSL
SCHEMBL31248043 0.90 ABCB1 (0.51) ABCB1CTSSCTSKCTSBCTSL
SCHEMBL24817612 0.88 CTSS (0.45) ABCB1CTSSCTSKCTSBCTSL
SCHEMBL31247975 0.87 ABCB1 (0.41) ABCB1CTSSCTSKCTSBCTSL
SCHEMBL30930720 0.84 ACE (0.42) ABCB1CTSSCTSKCTSBCTSL
SCHEMBL30892072 0.82 PSEN1 (0.42) ABCB1CTSSCTSKCTSBCTSL
SCHEMBL29757417 0.82 ITGB3 (0.47) ABCB1CTSSCTSKCTSBCTSL
SCHEMBL5096778 0.82 CTSS (0.58) ABCB1CTSSCTSKCTSBCTSL
SCHEMBL14264232 0.82 CTSS (0.58) ABCB1CTSSCTSKCTSBCTSL
SCHEMBL31501260 0.81 ABCB1 (0.41) ABCB1CTSSCTSKCTSBCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025092769-A1 PREPARATION METHOD FOR DUAL GIP AND GLP-1 RECEPTOR AGONIST 博瑞生物医药(苏州)股份有限公司 2025-05-08 — — WO claimed
CN-119350471-B Tenipout peptide synthesis method 中肽生化有限公司 2025-04-25 — — CN claimed
CN-119350471-A Tenipout peptide synthesis method 中肽生化有限公司 2025-01-24 — — CN claimed
CN-117946243-A Preparation method of Tirzepatide 江苏诺泰澳赛诺生物制药股份有限公司 2024-04-30 — — CN claimed
EP-4685157-A2 PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST Eli Lilly and Company (US) 2026-01-28 — — EP disclosed
EP-4685156-A2 PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST Eli Lilly and Company (US) 2026-01-28 — — EP disclosed
WO-2025092769-A1 PREPARATION METHOD FOR DUAL GIP AND GLP-1 RECEPTOR AGONIST 博瑞生物医药(苏州)股份有限公司 2025-05-08 — — WO disclosed
CN-119350471-B Tenipout peptide synthesis method 中肽生化有限公司 2025-04-25 — — CN disclosed
CN-119350471-A Tenipout peptide synthesis method 中肽生化有限公司 2025-01-24 — — CN disclosed
CN-118108791-A Synthetic method of Boc-Tyr (tBu) -Aib-Glu (OtBu) -Gly-OH 成都普康唯新生物科技有限公司 2024-05-31 — — CN disclosed
CN-118108791-A Synthetic method of Boc-Tyr (tBu) -Aib-Glu (OtBu) -Gly-OH 成都普康唯新生物科技有限公司 2024-05-31 — — CN disclosed
CN-117946243-A Preparation method of Tirzepatide 江苏诺泰澳赛诺生物制药股份有限公司 2024-04-30 — — CN disclosed
CN-117946243-A Preparation method of Tirzepatide 江苏诺泰澳赛诺生物制药股份有限公司 2024-04-30 — — CN disclosed
US-20230158468-A1 THREE RESIN REACTORS IN SERIES PEPTIDE SYNTHESIZER ELI LILLY AND COMPANY 2023-05-25 — — US disclosed
CN-115651075-B Synthesis method of Tirzepatide 杭州信海医药科技有限公司 2023-04-11 — — CN disclosed
CN-115651075-A Synthesis method of Tirzepatide 杭州信海医药科技有限公司 2023-01-31 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158468-A1 THREE RESIN REACTORS IN SERIES PEPTIDE SYNTHESIZER SRMS, PTMS, PNISR ABCB1 4643/4885CTSS 61/4885CTSK 623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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