Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25619098 | 0.80 | MPO (0.37) | MAPK1ALDH1A1TSHRTDP1SMN1; SMN2 | |
| SCHEMBL25625900 | 0.75 | HTT (0.35) | MEN1KMT2AMAPK1HTTTSHR | |
| SCHEMBL26319285 | 0.73 | MAPK1 (0.36) | MAPK1ALDH1A1NTRK1 | |
| SCHEMBL25619104 | 0.73 | MAPK1 (0.36) | MAPK1HTR2AHTR2BALDH1A1 | |
| SCHEMBL25619103 | 0.70 | UBE2M (0.34) | MAPK1CHRM2DRD2HTR2AHRH1 | |
| SCHEMBL25619087 | 0.69 | CACNA1G (0.37) | MEN1KMT2AMAPK1ABCB11CHRM2 | |
| SCHEMBL24875813 | 0.67 | SIGMAR1 (0.44) | MEN1KMT2AMAPK1CHRM2HTR2A | |
| SCHEMBL26319271 | 0.66 | MAPK1 (0.33) | MAPK1HTR2AALDH1A1 | |
| SCHEMBL24875216 | 0.66 | MAPK1 (0.34) | MAPK1HRH1 | |
| SCHEMBL24875175 | 0.66 | CYP19A1 (0.46) | KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097187-A1 | AMPK ACTIVATORS | KALLYOPE, INC. (US) | 2023-06-01 | — | — | WO | disclosed |