Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13906189 | 0.89 | KMT5A (0.36) | L3MBTL3HRH3KMT5A | |
| SCHEMBL20744455 | 0.77 | L3MBTL3 (0.46) | L3MBTL3HRH3JAK3KMT5A | |
| SCHEMBL19596383 | 0.75 | TEAD1 (0.47) | L3MBTL3JAK3 | |
| SCHEMBL15948708 | 0.73 | CHRNB2 (0.47) | L3MBTL3HRH3JAK3KMT5A | |
| SCHEMBL15624834 | 0.71 | GNAI3 (0.42) | L3MBTL3 | |
| SCHEMBL14971171 | 0.70 | HRH3 (0.36) | L3MBTL3HRH3 | |
| SCHEMBL22211389 | 0.70 | HRH3 (0.36) | L3MBTL3HRH3 | |
| SCHEMBL22211388 | 0.70 | HRH3 (0.36) | L3MBTL3HRH3 | |
| SCHEMBL9790975 | 0.69 | KMT5A (0.42) | L3MBTL3HRH3KMT5A | |
| SCHEMBL20070293 | 0.69 | HRH3 (0.35) | L3MBTL3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220134-A1 | PYRAZINE DERIVATIVES AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220129-A1 | BENZOYPARAZINE PYRAZINES ANE THEIR USES | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220137-A1 | PYRAZINE DERIVATIVES AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023098825-A1 | SOS1 INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 勤浩医药（苏州）有限公司 | 2023-06-08 | — | — | WO | disclosed |