Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5300656 | 0.82 | TP53 (0.46) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL5285062 | 0.78 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL13741192 | 0.76 | GPR84 (0.46) | — | |
| SCHEMBL5291000 | 0.76 | GGPS1 (0.40) | SIGMAR1ALDH1A1 | |
| SCHEMBL17301112 | 0.76 | FAAH (0.35) | ALDH1A1PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL5811446 | 0.74 | GGPS1 (0.45) | SLC6A2SLC6A4SLC6A3ADORA2AALDH1A1 | |
| SCHEMBL17737228 | 0.74 | PTGS1 (0.39) | ALDH1A1GABRA1GABRB2PTGS1PTGS2 | |
| SCHEMBL17301111 | 0.73 | FAAH (0.33) | ALDH1A1PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL5287386 | 0.73 | GGPS1 (0.47) | SLC6A2SLC6A4SLC6A3ADORA2AALDH1A1 | |
| SCHEMBL5304932 | 0.73 | GGPS1 (0.47) | SLC6A2SLC6A4SLC6A3ADORA2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11696912-B2 | Charged ion channel blockers and methods for use | Nocion Therapeutics, Inc. (US) | 2023-07-11 | — | — | US | disclosed |
| US-20230173093-A1 | CHARGE VARIANT LINKERS | SEAGEN INC (US) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11696912-B2 | Charged ion channel blockers and methods for use | TRPV1, ASIC1, TRPA1 | TAAR1 789/4885SLC6A2 541/4885SIGMAR1 726/4885 |
| US-20230173093-A1 | CHARGE VARIANT LINKERS | SSB, UACA, CDA | TAAR1 3918/4885SLC6A2 1885/4885SIGMAR1 4535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.