Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621830 | 0.90 | L3MBTL1 (0.56) | L3MBTL1MAPTNPSR1TDP1CYP1A2 | |
| SCHEMBL821928 | 0.88 | CYP1A2 (0.62) | L3MBTL1MAPTNPSR1TDP1CYP1A2 | |
| SCHEMBL8625705 | 0.88 | MEN1 (0.48) | L3MBTL1MAPTNPSR1CYP1A2CYP2C19 | |
| SCHEMBL8623222 | 0.87 | ALDH1A1 (0.55) | L3MBTL1MAPTTDP1CYP1A2CYP2C19 | |
| SCHEMBL10619437 | 0.85 | ADRB2 (0.54) | L3MBTL1ALDH1A1RAB9ALMNAMEN1 | |
| SCHEMBL2579282 | 0.83 | KCNA3 (0.54) | L3MBTL1TDP1ALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL2799654 | 0.80 | DRD2 (0.51) | L3MBTL1MAPTNPSR1ALDH1A1RAB9A | |
| SCHEMBL8673227 | 0.79 | LMNA (0.44) | L3MBTL1MAPTNPSR1ALDH1A1HPGD | |
| SCHEMBL30537732 | 0.78 | MAPK1 (0.48) | L3MBTL1MAPTNPSR1TDP1CYP1A2 | |
| SCHEMBL29198750 | 0.77 | NPC1 (0.33) | MAPTCYP1A2CYP2C19CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183458-A1 | NON-ACTIVE SULFUR CONTAINING FUNCTIONAL SILANES FOR SILICA COMPOUNDS | THE GOODYEAR TIRE & RUBBER COMPANY | 2023-06-15 | — | — | US | disclosed |