Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.97 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.97 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.97 |
| ▸ | CES1 | P23141 | 4/20 | 0.97 |
| ▸ | EED | O75530 | 4/20 | 0.97 |
| ▸ | SUZ12 | Q15022 | 4/20 | 0.97 |
| ▸ | EZH2 | Q15910 | 4/20 | 0.97 |
| ▸ | CES2 | O00748 | 3/20 | 0.97 |
| ▸ | MAPT | P10636 | 3/20 | 0.97 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.97 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.97 |
| ▸ | KDM1A | O60341 | 2/20 | 0.97 |
| ▸ | BLM | P54132 | 2/20 | 0.97 |
| ▸ | POLB | P06746 | 2/20 | 0.97 |
| ▸ | NSD1 | Q96L73 | 2/20 | 0.97 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.97 |
| ▸ | NQO1 | P15559 | 4/20 | 0.52 |
| ▸ | POR | P16435 | 4/20 | 0.52 |
| ▸ | IDO1 | P14902 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tanshinone I SCHEMBL14993883 | 0.98 | TDP1 (1.00) | TDP1HIF1AEPAS1CES1EED | |
| Tanshinone I SCHEMBL244391 | 0.98 | TDP1 (1.00) | TDP1HIF1AEPAS1CES1EED | |
| Tanshinone I SCHEMBL3664228 | 0.93 | TDP1 (0.89) | TDP1HIF1AEPAS1CES1EED | |
| SCHEMBL16023778 | 0.88 | HIF1A (0.81) | TDP1HIF1AEPAS1CES1EED | |
| SCHEMBL29411323 | 0.88 | HIF1A (0.81) | TDP1HIF1AEPAS1CES1EED | |
| Isotanshinone Ii SCHEMBL30035659 | 0.88 | HIF1A (0.81) | TDP1HIF1AEPAS1CES1EED | |
| Tanshinone I SCHEMBL728081 | 0.84 | EED (0.73) | TDP1HIF1AEPAS1CES1EED | |
| SCHEMBL16152288 | 0.83 | TDP1 (0.73) | TDP1HIF1AEPAS1CES1EED | |
| SCHEMBL29520853 | 0.83 | TDP1 (0.73) | TDP1HIF1AEPAS1CES1EED | |
| SCHEMBL30381335 | 0.83 | EED (0.73) | TDP1HIF1AEPAS1CES1EED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 379 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118240001-A | Preparation method of tanshinone IIA | 上海上药第一生化药业有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118206613-A | Refining method of tanshinone IIA analogue | 上海上药第一生化药业有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-118165061-A | Method for preparing high-purity tanshinone IIA sodium sulfonate and content detection method thereof | 康诺瑞达(福建)新药开发有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-117986317-A | Preparation method of 1, 2-dehydrotanshinone IIA | 上海上药第一生化药业有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-117924405-A | Refining method of tanshinone IIA sodium sulfonate | 上海上药第一生化药业有限公司 | 2024-04-26 | — | — | CN | claimed |
| WO-2024056995-A1 | COMBINATIONS AND PHARMACEUTICAL COMPOSITIONS COMPRISING A PI3K/AKT/MTOR PATHWAY INHIBITING COMPOUND | ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) | 2024-03-21 | — | — | WO | claimed |
| CN-117338736-A | Pharmaceutical composition, tanshinone IIA sodium sulfonate tablet, and preparation method and application thereof | 上海上药第一生化药业有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-117205327-A | Tanshinone IIA sodium sulfonate pharmaceutical composition, slow-release microsphere, preparation method and application thereof | 上海上药第一生化药业有限公司 | 2023-12-12 | — | — | CN | claimed |
| CN-117064856-A | Preparation method of polyphenol-amino acid drug-loaded nano-particles | 四川大学 | 2023-11-17 | — | — | CN | claimed |
| CN-116640706-B | Fermentation process of gamma-polyglutamic acid and culture medium thereof | 山东土秀才生物科技有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-1698598-A | Tanshinone IIA sodium sulfonate transfusion liquid, its preparation method and photophobic outer package | DIAO YONG (CN) | 2005-11-23 | — | — | CN | claimed |
| CN-1686103-A | Medicinal composition containing tanshinon II A sodium sulfonate and its quality control method | UNIV SICHUAN (CN) | 2005-10-26 | — | — | CN | claimed |
| CN-1686105-A | Danshinone II A sodium sulphonate freeze dried powder injection agent and its preparation method | LIU XIN (CN) | 2005-10-26 | — | — | CN | claimed |
| CN-1640391-A | Tanshinon IIA sulfonic acid sodium glucose injection liquid and its preparing method | XIJIE MEDICINE RES & DEV CO LT (CN) | 2005-07-20 | — | — | CN | claimed |
| CN-1634589-A | Injection using invert sugar water solution as carrier | YANG XIHONG (CN) | 2005-07-06 | — | — | CN | claimed |
| CN-1634024-A | Tanshinone IIA sodium sulfonate for injection and its preparation method | KUNMING XIJIE MEDICAL RES AND (CN) | 2005-07-06 | — | — | CN | claimed |
| CN-1623538-A | Tanshinone II A sulfonic acid or tanshinone II A sodium sulfonate freeze-dried powder injection and its preparation method | LIU LI (CN) | 2005-06-08 | — | — | CN | claimed |
| CN-1555791-A | Tanshinone II A sodium sulfonate powder injection agent and its preparation method | 昆明同持医药研究有限公司 | 2004-12-22 | — | — | CN | claimed |
| CN-1457784-A | Method for producing xinnaoning injectin containing chuanxiong rhizome and red sage root extract | GUO DONGYU (CN) | 2003-11-26 | — | — | CN | claimed |
| CN-1067586-C | Composite medicinal injection for hemiparalysis | LI GUORONG (CN) | 2001-06-27 | — | — | CN | claimed |