Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.89 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.89 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.89 |
| ▸ | CES1 | P23141 | 4/20 | 0.89 |
| ▸ | EED | O75530 | 4/20 | 0.89 |
| ▸ | SUZ12 | Q15022 | 4/20 | 0.89 |
| ▸ | EZH2 | Q15910 | 4/20 | 0.89 |
| ▸ | CES2 | O00748 | 3/20 | 0.89 |
| ▸ | MAPT | P10636 | 3/20 | 0.89 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.89 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.89 |
| ▸ | KDM1A | O60341 | 2/20 | 0.89 |
| ▸ | BLM | P54132 | 2/20 | 0.89 |
| ▸ | POLB | P06746 | 2/20 | 0.89 |
| ▸ | NSD1 | Q96L73 | 2/20 | 0.89 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.89 |
| ▸ | NQO1 | P15559 | 4/20 | 0.52 |
| ▸ | POR | P16435 | 4/20 | 0.52 |
| ▸ | IDO1 | P14902 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tanshinone I SCHEMBL14993883 | 0.94 | TDP1 (1.00) | TDP1HIF1AEPAS1CES1EED | |
| Tanshinone I SCHEMBL244391 | 0.94 | TDP1 (1.00) | TDP1HIF1AEPAS1CES1EED | |
| Tanshinone I SCHEMBL2564448 | 0.93 | TDP1 (0.97) | TDP1HIF1AEPAS1CES1EED | |
| SCHEMBL29411323 | 0.85 | HIF1A (0.81) | TDP1HIF1AEPAS1CES1EED | |
| SCHEMBL16023778 | 0.85 | HIF1A (0.81) | TDP1HIF1AEPAS1CES1EED | |
| Isotanshinone Ii SCHEMBL30035659 | 0.85 | HIF1A (0.81) | TDP1HIF1AEPAS1CES1EED | |
| Tanshinone I SCHEMBL728081 | 0.83 | EED (0.73) | TDP1HIF1AEPAS1CES1EED | |
| SCHEMBL16152288 | 0.80 | TDP1 (0.73) | TDP1HIF1AEPAS1CES1EED | |
| SCHEMBL29520853 | 0.80 | TDP1 (0.73) | TDP1HIF1AEPAS1CES1EED | |
| SCHEMBL30381335 | 0.80 | EED (0.73) | TDP1HIF1AEPAS1CES1EED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9283256-B2 | Antibacterial composition comprising Salvia extracts | BOTANIC CENTURY (BEIJING) CO. LTD. (CN) | 2016-03-15 | — | — | US | disclosed |
| US-20100292318-A1 | ANTIBACTERIAL COMPOSITION COMPRISING SALVIA EXTRACTS | BOTANIC CENTURY (BEIJING) CO. LTD. (CN) | 2010-11-18 | — | — | US | disclosed |
| EP-2211883-A1 | ANTIBACTERIAL COMPOSITION COMPRISING SALVIA EXTRACTS | Botanic Century (Beijing) Co. Ltd (CN) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009050451-A1 | ANTIBACTERIAL COMPOSITION COMPRISING SALVIA EXTRACTS | BOTANIC CENTURY (BEIJING) CO. LTD (CN) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292318-A1 | ANTIBACTERIAL COMPOSITION COMPRISING SALVIA EXTRACTS | SRI, PSD, SRRT | TDP1 3857/4885HIF1A 596/4885EPAS1 2677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.