Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.81 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.81 |
| ▸ | CES1 | P23141 | 4/20 | 0.81 |
| ▸ | MAPT | P10636 | 4/20 | 0.81 |
| ▸ | CES2 | O00748 | 3/20 | 0.81 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.81 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.81 |
| ▸ | KDM1A | O60341 | 2/20 | 0.81 |
| ▸ | BLM | P54132 | 2/20 | 0.81 |
| ▸ | EED | O75530 | 2/20 | 0.81 |
| ▸ | POLB | P06746 | 2/20 | 0.81 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.81 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.81 |
| ▸ | NSD1 | Q96L73 | 2/20 | 0.81 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.81 |
| ▸ | NQO1 | P15559 | 4/20 | 0.53 |
| ▸ | POR | P16435 | 4/20 | 0.53 |
| ▸ | IDO1 | P14902 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tanshinone I SCHEMBL244391 | 0.90 | TDP1 (1.00) | HIF1AEPAS1TDP1CES1MAPT | |
| Tanshinone I SCHEMBL14993883 | 0.90 | TDP1 (1.00) | HIF1AEPAS1TDP1CES1MAPT | |
| SCHEMBL29411323 | 0.88 | HIF1A (0.81) | HIF1AEPAS1TDP1CES1MAPT | |
| SCHEMBL16023778 | 0.88 | HIF1A (0.81) | HIF1AEPAS1TDP1CES1MAPT | |
| Tanshinone I SCHEMBL2564448 | 0.88 | TDP1 (0.97) | HIF1AEPAS1TDP1CES1MAPT | |
| Tanshinone I SCHEMBL3664228 | 0.85 | TDP1 (0.89) | HIF1AEPAS1TDP1CES1MAPT | |
| Tanshinone I SCHEMBL728081 | 0.77 | EED (0.73) | HIF1AEPAS1TDP1CES1MAPT | |
| SCHEMBL30381335 | 0.75 | EED (0.73) | HIF1AEPAS1TDP1CES1MAPT | |
| SCHEMBL29520853 | 0.75 | TDP1 (0.73) | HIF1AEPAS1TDP1CES1MAPT | |
| SCHEMBL16152288 | 0.75 | TDP1 (0.73) | HIF1AEPAS1TDP1CES1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119380826-B | Chinese patent medicine network pharmacology analysis method and model construction method based on multiscale information entropy | 首都医科大学附属北京朝阳医院 | 2025-04-08 | — | — | CN | disclosed |
| CN-119380826-A | Chinese patent medicine network pharmacology analysis method and model construction method based on multiscale information entropy | 首都医科大学附属北京朝阳医院 | 2025-01-28 | — | — | CN | disclosed |
| US-20230390352-A1 | COMPOSITION COMPRISING SALVIA MILTIORRHIZA EXTRACT AS ACTIVE INGREDIENT FOR PREVENTION AND TREATMENT OF DEPRESSION IN MENOPAUSAL WOMEN | UNDBIO.CO.,LTD (KR) | 2023-12-07 | — | — | US | disclosed |
| CN-113318205-B | Traditional Chinese medicine composition for treating pleural effusion and pericardial effusion | 吉林省中医药科学院（吉林省中医药科学院第一临床医院） | 2022-10-28 | — | — | CN | disclosed |