Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 5/20 | 0.73 |
| ▸ | SUZ12 | Q15022 | 5/20 | 0.73 |
| ▸ | EZH2 | Q15910 | 5/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.73 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.73 |
| ▸ | CES2 | O00748 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | CES1 | P23141 | 3/20 | 0.73 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.73 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.73 |
| ▸ | KDM1A | O60341 | 2/20 | 0.73 |
| ▸ | BLM | P54132 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.73 |
| ▸ | NSD1 | Q96L73 | 2/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.73 |
| ▸ | NQO1 | P15559 | 4/20 | 0.44 |
| ▸ | POR | P16435 | 4/20 | 0.44 |
| ▸ | IDO1 | P14902 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tanshinone I SCHEMBL14993883 | 0.86 | TDP1 (1.00) | EEDSUZ12EZH2HIF1AEPAS1 | |
| Tanshinone I SCHEMBL244391 | 0.86 | TDP1 (1.00) | EEDSUZ12EZH2HIF1AEPAS1 | |
| Tanshinone I SCHEMBL2564448 | 0.84 | TDP1 (0.97) | EEDSUZ12EZH2HIF1AEPAS1 | |
| Tanshinone I SCHEMBL3664228 | 0.83 | TDP1 (0.89) | EEDSUZ12EZH2HIF1AEPAS1 | |
| SCHEMBL16023778 | 0.77 | HIF1A (0.81) | EEDSUZ12EZH2HIF1AEPAS1 | |
| SCHEMBL29411323 | 0.77 | HIF1A (0.81) | EEDSUZ12EZH2HIF1AEPAS1 | |
| Isotanshinone Ii SCHEMBL30035659 | 0.77 | HIF1A (0.81) | EEDSUZ12EZH2HIF1AEPAS1 | |
| SCHEMBL30381335 | 0.75 | EED (0.73) | EEDSUZ12EZH2HIF1AEPAS1 | |
| SCHEMBL16152288 | 0.75 | TDP1 (0.73) | EEDSUZ12EZH2HIF1AEPAS1 | |
| SCHEMBL29520853 | 0.75 | TDP1 (0.73) | EEDSUZ12EZH2HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4657714-B2 | — | — | 2011-03-23 | — | — | JP | claimed |
| US-20050037094-A1 | Composition for heart disease, its active ingredients, method to prepare same and uses thereof | TIANJIN TASLY PHARMACEUTICAL CO., LTD., CHINA (CN) | 2005-02-17 | — | — | US | claimed |
| WO-2004012651-A2 | COMPOSITION FOR HEART DISEASE, METHOD TO PREPARE SAME AND USES THEREOF | TIANJIN TASLY PHARMACEUTICAL CO., LTD., CHINA (US) | 2004-02-12 | — | — | WO | claimed |
| EP-1388344-A1 | Composition comprising Salvia Miltiorrhizae, Ginseng, Borneol for treating heart disease, and cerebrovascular diseases | Tianjin Tasly Pharmaceutical Co., Ltd., China (CN) | 2004-02-11 | — | — | EP | claimed |
| CN-108030817-B | Preparation method of Yiganshukang capsule for treating hepatitis B | 陕西东科制药有限责任公司 | 2021-04-20 | — | — | CN | disclosed |
| CN-110652496-A | Solid dispersion of cryptotanshinone and preparation method and application thereof | 中山大学 | 2020-01-07 | — | — | CN | disclosed |
| CN-108030817-A | A kind of preparation method of Alpha interferon | 陕西东科制药有限责任公司 | 2018-05-15 | — | — | CN | disclosed |
| US-9895405-B2 | Use of radix salviae miltiorrhizae (danshen) or its preparations in preparation of drugs for treating diseases related to hepatic fibrosis | TASLY PHARMACEUTICAL GROUP CO., LTD. (CN) | 2018-02-20 | — | — | US | disclosed |
| US-20150044310-A1 | USE OF RADIX SALVIAE MILTIORRHIZAE (DANSHEN) OR ITS PREPARATIONS IN PREPARATION OF DRUGS FOR TREATING DISEASES RELATED TO HEPATIC FIBROSIS | TASLY PHARMACEUTICAL GROUP CO., LTD. (CN) | 2015-02-12 | — | — | US | disclosed |
| EP-2801365-A1 | USES OF DANSHEN OR DANSHEN PREPARATION IN PREPARATION OF DRUGS FOR TREATING DISEASES RELATED TO HEPATIC FIBROSIS | Tasly Pharmaceutical Group Co., Ltd. (CN) | 2014-11-12 | — | — | EP | disclosed |
| US-8883228-B2 | Composition for heart disease, its active ingredients, method to prepare same and uses thereof | TASLY PHARMACEUTICAL GROUP CO. LTD. (CN) | 2014-11-11 | — | — | US | disclosed |
| EP-1388344-B1 | Composition comprising Salvia Miltiorrhiza, Ginseng, Borneol for treating heart disease, and cerebrovascular diseases | TASLY PHARMACEUTICAL GROUP CO (CN) | 2014-03-12 | — | — | EP | disclosed |
| US-20100136146-A1 | COMPOSITION FOR HEART DISEASE, ITS ACTIVE INGREDIENTS, METHOD TO PREPARE SAME AND USES THEREOF | TASLY PHARMACEUTICAL GROUP CO. LTD. (CN) | 2010-06-03 | — | — | US | disclosed |
| US-20050037094-A1 | Composition for heart disease, its active ingredients, method to prepare same and uses thereof | TIANJIN TASLY PHARMACEUTICAL CO., LTD., CHINA (CN) | 2005-02-17 | — | — | US | disclosed |
| WO-2004012651-A2 | COMPOSITION FOR HEART DISEASE, METHOD TO PREPARE SAME AND USES THEREOF | TIANJIN TASLY PHARMACEUTICAL CO., LTD., CHINA (US) | 2004-02-12 | — | — | WO | disclosed |
| EP-1388344-A1 | Composition comprising Salvia Miltiorrhizae, Ginseng, Borneol for treating heart disease, and cerebrovascular diseases | Tianjin Tasly Pharmaceutical Co., Ltd., China (CN) | 2004-02-11 | — | — | EP | disclosed |