Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.81 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.81 |
| ▸ | CES1 | P23141 | 4/20 | 0.81 |
| ▸ | MAPT | P10636 | 4/20 | 0.81 |
| ▸ | CES2 | O00748 | 3/20 | 0.81 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.81 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.81 |
| ▸ | KDM1A | O60341 | 2/20 | 0.81 |
| ▸ | BLM | P54132 | 2/20 | 0.81 |
| ▸ | EED | O75530 | 2/20 | 0.81 |
| ▸ | POLB | P06746 | 2/20 | 0.81 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.81 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.81 |
| ▸ | NSD1 | Q96L73 | 2/20 | 0.81 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.81 |
| ▸ | IDO1 | P14902 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16023778 | 1.00 | HIF1A (0.81) | HIF1AEPAS1TDP1CES1MAPT | |
| Tanshinone I SCHEMBL244391 | 0.90 | TDP1 (1.00) | HIF1AEPAS1TDP1CES1MAPT | |
| Tanshinone I SCHEMBL14993883 | 0.90 | TDP1 (1.00) | HIF1AEPAS1TDP1CES1MAPT | |
| Tanshinone I SCHEMBL2564448 | 0.88 | TDP1 (0.97) | HIF1AEPAS1TDP1CES1MAPT | |
| Isotanshinone Ii SCHEMBL30035659 | 0.88 | HIF1A (0.81) | HIF1AEPAS1TDP1CES1MAPT | |
| Tanshinone I SCHEMBL3664228 | 0.85 | TDP1 (0.89) | HIF1AEPAS1TDP1CES1MAPT | |
| Tanshinone I SCHEMBL728081 | 0.77 | EED (0.73) | HIF1AEPAS1TDP1CES1MAPT | |
| SCHEMBL16152288 | 0.75 | TDP1 (0.73) | HIF1AEPAS1TDP1CES1MAPT | |
| SCHEMBL30381335 | 0.75 | EED (0.73) | HIF1AEPAS1TDP1CES1MAPT | |
| SCHEMBL29520853 | 0.75 | TDP1 (0.73) | HIF1AEPAS1TDP1CES1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117180439-A | Compounds and compositions for treating hemorrhagic disorders | 中国科学院上海药物研究所 | 2023-12-08 | — | — | CN | claimed |
| WO-2023232090-A1 | COMPOUND FOR TREATING HEMORRHAGIC DISEASES AND COMPOSITION THEREOF | 中国科学院上海药物研究所 | 2023-12-07 | — | — | WO | claimed |
| CN-119380826-B | Chinese patent medicine network pharmacology analysis method and model construction method based on multiscale information entropy | 首都医科大学附属北京朝阳医院 | 2025-04-08 | — | — | CN | disclosed |
| CN-119380826-A | Chinese patent medicine network pharmacology analysis method and model construction method based on multiscale information entropy | 首都医科大学附属北京朝阳医院 | 2025-01-28 | — | — | CN | disclosed |
| CN-119365200-A | Compounds and compositions for treating hemorrhagic disorders | 中国科学院上海药物研究所 | 2025-01-24 | — | — | CN | disclosed |
| CN-116994653-B | Sepsis diagnosis model construction method, compound screening method and electronic equipment | 南方医科大学南方医院 | 2024-09-10 | — | — | CN | disclosed |
| CN-118217325-A | Danzhiqing tablet dry extract and preparation method thereof | 华润三九医药股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-117180439-A | Compounds and compositions for treating hemorrhagic disorders | 中国科学院上海药物研究所 | 2023-12-08 | — | — | CN | disclosed |
| WO-2023232090-A1 | COMPOUND FOR TREATING HEMORRHAGIC DISEASES AND COMPOSITION THEREOF | 中国科学院上海药物研究所 | 2023-12-07 | — | — | WO | disclosed |
| US-20230390352-A1 | COMPOSITION COMPRISING SALVIA MILTIORRHIZA EXTRACT AS ACTIVE INGREDIENT FOR PREVENTION AND TREATMENT OF DEPRESSION IN MENOPAUSAL WOMEN | UNDBIO.CO.,LTD (KR) | 2023-12-07 | — | — | US | disclosed |
| CN-116994653-A | Sepsis diagnosis model construction method, compound screening method and electronic equipment | 南方医科大学南方医院 | 2023-11-03 | — | — | CN | disclosed |
| US-20230147718-A1 | COMPOSITION FOR CANCER PREVENTION OR TREATMENT, CONTAINING, AS ACTIVE INGREDIENT, SALVIANOLIC ACID B OR TANSHINONE I | GJMEDI (KR) | 2023-05-11 | — | — | US | disclosed |
| CN-112120970-B | Chinese herbal medicine essential oil composition with permeation promoting effect, preparation method and application thereof | 上海相宜本草化妆品股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115590986-A | Preparation method and application of lipid nano microbubble ultrasound contrast agent carrying tanshinone IIA | 杭州师范大学附属医院（杭州市第二人民医院）（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-115487280-A | Traditional Chinese medicine composition for relieving alcoholism, protecting liver and promoting liver regeneration, preparation and preparation method thereof | 浙江中医药大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-114948978-A | Pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2022-08-30 | — | — | CN | disclosed |
| CN-114392298-A | Double-fermentation extraction process and preparation method of salvia miltiorrhiza root and cotton rose hibiscus leaf | 云南柏脉生物科技有限公司昆明分公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-114176171-A | Feed additive for increasing yield of poultry and preparation method thereof | 河南省奥邦生物科技有限公司 | 2022-03-15 | — | — | CN | disclosed |