Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.49 |
| ▸ | FOS | P01100 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | INPPL1 | O15357 | 3/20 | 0.44 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28873855 | 0.83 | GABRA1 (0.51) | ALOX15ALOX12INPPL1INPP5AAKT1 | |
| SCHEMBL25019645 | 0.83 | INPPL1 (0.47) | LDHAINPPL1INPP5AAKT1ALDH1A1 | |
| SCHEMBL806723 | 0.82 | CA2 (0.63) | LDHAALOX15ALOX12FOSTTR | |
| SCHEMBL25022603 | 0.81 | INPPL1 (0.46) | LDHAINPPL1INPP5AAKT1ALDH1A1 | |
| SCHEMBL4387213 | 0.81 | ALDH1A1 (0.42) | LDHAALOX15ALOX12INPPL1INPP5A | |
| SCHEMBL28679707 | 0.80 | KMT2A (0.45) | LDHAALOX15ALDH1A1 | |
| SCHEMBL16001567 | 0.78 | ALOX15 (0.75) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL2592240 | 0.78 | ALDH1A1 (0.69) | ALDH1A1HTTNPC1LMNA | |
| SCHEMBL14379934 | 0.76 | CYP1A2 (0.51) | INPPL1INPP5AAKT1ALDH1A1CA2 | |
| SCHEMBL12775553 | 0.76 | LDHA (0.51) | LDHAALOX15ALOX12FOSTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151024-A1 | STING AGONISTIC COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2023-05-18 | — | — | US | disclosed |
| US-20230151024-A1 | STING AGONISTIC COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2023-05-18 | — | — | US | disclosed |
| US-20230141284-A1 | CANCER THERAPEUTIC METHOD | ONO PHARMACEUTICAL CO., LTD. (JP) | 2023-05-11 | — | — | US | disclosed |
| US-20230141284-A1 | CANCER THERAPEUTIC METHOD | ONO PHARMACEUTICAL CO., LTD. (JP) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230141284-A1 | CANCER THERAPEUTIC METHOD | STING1, CGAS, IFNAR1 | LDHA 3803/4885ALOX15 350/4885ALOX12 454/4885 |
| US-20230151024-A1 | STING AGONISTIC COMPOUND | STING1, CGAS, TLR1 | LDHA 4640/4885ALOX15 1264/4885ALOX12 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.