SCHEMBL25660591

SCHEMBL25660591

C=CCOC(=O)NCC(N)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GFPT1 Q06210 1/20 0.45
GRIK1 P39086 2/20 0.40
GRIK2 Q13002 2/20 0.40
DDAH1 O94760 1/20 0.38
CASP1 P29466 7/20 0.38
MAPT P10636 1/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SLC1A3 P43003 1/20 0.33
SLC1A1 P43005 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17324271 1.00 GFPT1 (0.45) GFPT1GRIK1GRIK2DDAH1CASP1
Hydrochloric Acid SCHEMBL31496724 0.98 GFPT1 (0.44) GFPT1GRIK1GRIK2DDAH1CASP1
SCHEMBL16446798 0.89 GFPT1 (0.40) GFPT1GRIK1GRIK2DDAH1CASP1
SCHEMBL15746590 0.84 DDAH1 (0.39) GFPT1GRIK1GRIK2DDAH1CASP1
SCHEMBL24185361 0.83 DDAH1 (0.46) GRIK1GRIK2DDAH1CASP1MAPT
SCHEMBL7194971 0.81 DDAH1 (0.57) GRIK1GRIK2DDAH1CASP1MEN1
SCHEMBL22281180 0.81 DDAH1 (0.57) GRIK1GRIK2DDAH1CASP1MEN1
SCHEMBL28297586 0.81 DDAH1 (0.57) GRIK1GRIK2DDAH1CASP1MEN1
SCHEMBL18159716 0.81 TDP1 (0.39) CASP1MAPTCACNA1BAPBA1MEN1
SCHEMBL1700571 0.80 ARG1 (0.37) GRIK1GRIK2DDAH1CASP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF RAYZEBIO, INC. 2023-05-25 US disclosed
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF RAYZEBIO, INC. 2023-05-25 US disclosed
CN-113226375-A Methods and compositions 英国研究与创新署 2021-08-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF PAICS, LNPEP, DNPEP GFPT1 638/4885GRIK1 2914/4885GRIK2 3197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.