Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16239239 | 0.88 | RAB9A (0.41) | NR4A2SMN1; SMN2LMNAMAPTBRD4 | |
| SCHEMBL18896381 | 0.83 | PDE3B (0.36) | NR4A2PDE3BPDE3ASMN1; SMN2LMNA | |
| SCHEMBL17967309 | 0.82 | PDE3B (0.33) | NR4A2PDE3BPDE3ASMN1; SMN2LMNA | |
| SCHEMBL18010785 | 0.79 | ALDH1A1 (0.47) | NR4A2SMN1; SMN2LMNAMAPTBRD4 | |
| SCHEMBL15084306 | 0.79 | KDM4E (0.43) | LMNAMAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL17967300 | 0.77 | KMT2A (0.41) | NR4A2LMNARAB9ANPC1KDM4E | |
| SCHEMBL2601037 | 0.77 | PLA2G4A (0.38) | NR4A2SMN1; SMN2LMNAMAPTBRD4 | |
| SCHEMBL17928514 | 0.75 | TSHR (0.39) | NR4A2LMNABRD4RAB9AKDM4E | |
| SCHEMBL16453350 | 0.74 | PDE10A (0.53) | — | |
| SCHEMBL19041053 | 0.74 | LMNA (0.45) | NR4A2SMN1; SMN2LMNAMAPTBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083162-A1 | POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION THEREOF | 南京艾迪医药科技有限公司 | 2023-05-19 | — | — | WO | disclosed |