Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14808369 | 0.86 | HSD17B1 (0.40) | RAB9ALMNAKMT2ASMN1; SMN2HTT | |
| SCHEMBL4295114 | 0.85 | RAB9A (0.37) | RAB9ALMNAKMT2ASMN1; SMN2HTT | |
| SCHEMBL18280409 | 0.85 | CSNK2A1 (0.50) | RAB9ALMNAKMT2ASMN1; SMN2HTT | |
| SCHEMBL23298982 | 0.83 | RAB9A (0.37) | RAB9ALMNAKMT2ASMN1; SMN2HTT | |
| SCHEMBL25669476 | 0.80 | NR4A2 (0.46) | LMNAHTTNPSR1ALDH1A1HPGD | |
| SCHEMBL6498251 | 0.78 | ALDH1A1 (0.48) | LMNAKMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL27825242 | 0.78 | CYP3A4 (0.48) | RAB9AKMT2ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL302204 | 0.77 | CSNK2A1 (0.48) | RAB9ALMNAKMT2ASMN1; SMN2HTT | |
| SCHEMBL28610612 | 0.77 | DGAT1 (0.39) | RAB9ALMNAKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21407748 | 0.77 | CES2 (0.44) | RAB9ALMNAKMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183180-A1 | PROCESS OF MAKING ROXADUSTAT | SUZHOU PENGXU PHARMATECH CO., LTD. (CN) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183180-A1 | PROCESS OF MAKING ROXADUSTAT | CYP2B6, UGT1A6, CYP2D6 | RAB9A 2831/4885LMNA 394/4885KMT2A 1095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.