Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | BCR | P11274 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.32 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24054370 | 0.83 | KMT2A (0.56) | SMN1; SMN2KMT2AMAPTRECQLALDH1A1 | |
| SCHEMBL30166311 | 0.83 | KMT2A (0.56) | SMN1; SMN2KMT2AMAPTRECQLALDH1A1 | |
| SCHEMBL24054153 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2KMT2AMAPTALDH1A1ABL1 | |
| SCHEMBL25695023 | 0.67 | KMT2A (0.45) | SMN1; SMN2KMT2AMAPTALDH1A1HTT | |
| SCHEMBL30166321 | 0.66 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMAPTALDH1A1ABL1 | |
| SCHEMBL24054006 | 0.66 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMAPTALDH1A1ABL1 | |
| SCHEMBL25695425 | 0.65 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL16543698 | 0.65 | JUN (0.49) | SMN1; SMN2RECQLALDH1A1KDM4EHPGD | |
| SCHEMBL25281989 | 0.64 | ALDH1A1 (0.40) | SMN1; SMN2KMT2AMAPTALDH1A1HTT | |
| SCHEMBL31205699 | 0.64 | RPS6KA5 (0.52) | SMN1; SMN2KMT2AMAPTALDH1A1RPS6KA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203019-A1 | Piperazine Cyclic Ureas | SIRONAX (BEIJING) CO., LTD. (CN) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203019-A1 | Piperazine Cyclic Ureas | RIPK1, RIPK3, RIPK4 | SMN1; SMN2 2977/4885KMT2A 4588/4885MAPT 2881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.