SCHEMBL25801450

SCHEMBL25801450

c1ccc(N2CN(c3cccc4c3oc3ccccc34)c3ccccc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
KDM4E B2RXH2 2/20 0.38
HPGD P15428 2/20 0.38
HCRTR1 O43613 1/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PRKDC P78527 5/20 0.38
ALOX5 P09917 3/20 0.37
PIK3CD O00329 1/20 0.37
PIK3CB P42338 1/20 0.37
ALDH1A1 P00352 3/20 0.37
PPARG P37231 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
NR2E3 Q9Y5X4 1/20 0.37
NCOR2 Q9Y618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24913473 0.85 TSHR (0.41) MAPTMEN1KMT2AKDM4EHPGD
SCHEMBL24913774 0.77 MEN1 (0.37) MAPTMEN1KMT2AKDM4EHPGD
SCHEMBL31122827 0.76 PRKDC (0.35) MEN1KMT2AHPGDTP53PRKDC
SCHEMBL30261935 0.75 SIGMAR1 (0.48) MAPTMEN1KMT2AKDM4EHPGD
SCHEMBL12153468 0.75 SIGMAR1 (0.48) MAPTMEN1KMT2AKDM4EHPGD
SCHEMBL17367755 0.74 KDM4E (0.46) MAPTMEN1KMT2AKDM4EHPGD
SCHEMBL20887127 0.72 PRKDC (0.54) MAPTMEN1KMT2ATSHRMAPK1
SCHEMBL15462296 0.72 KDM4E (0.47) MAPTMEN1KMT2AKDM4EHPGD
SCHEMBL24851113 0.72 MEN1 (0.39) MAPTMEN1KMT2AKDM4EHPGD
SCHEMBL20887148 0.72 BRD4 (0.43) HPGDTP53TSHRPRKDCPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-06-25 US disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20240025934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 US disclosed
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-11778897-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-03 US disclosed
US-20230309396-A1 Host Materials for Electroluminscent Devices UNIVERSAL DISPLAY CORPORATION 2023-09-28 US disclosed
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-11758804-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-12 US disclosed
US-11753425-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-12 US disclosed
US-11706980-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-18 US disclosed
US-20230192738-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11706980-B2 Host materials for electroluminescent devices CRHR1, CRHR2, CRH MAPT 4168/4885MEN1 1660/4885KMT2A 4290/4885
US-20230309396-A1 Host Materials for Electroluminscent Devices CRHR1, CRHR2, CRH MAPT 4201/4885MEN1 1926/4885KMT2A 4331/4885
US-20240025934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, RO60, LIFR MAPT 3432/4885MEN1 1822/4885KMT2A 1352/4885
US-11758804-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 MAPT 2043/4885MEN1 3363/4885KMT2A 4518/4885
US-11778897-B2 Organic electroluminescent materials and devices LIFR, LBR, ZFR MAPT 4002/4885MEN1 3677/4885KMT2A 2291/4885
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OXGR1, OCIAD1 MAPT 1880/4885MEN1 3516/4885KMT2A 2236/4885
US-11864458-B2 Organic electroluminescent materials and devices RAP1A, L1CAM, SOD1 MAPT 3446/4885MEN1 2774/4885KMT2A 1364/4885
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP MAPT 1707/4885MEN1 4145/4885KMT2A 4312/4885
US-12022727-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 MAPT 2502/4885MEN1 2962/4885KMT2A 4442/4885
US-11753425-B2 Organic electroluminescent materials and devices SSB, RO60, LIFR MAPT 3432/4885MEN1 1822/4885KMT2A 1352/4885
US-20230192738-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRM1, OPRD1, OXER1 MAPT 2859/4885MEN1 1982/4885KMT2A 3330/4885
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, LBR, ZFR MAPT 4002/4885MEN1 3677/4885KMT2A 2291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.