SCHEMBL2570967

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2567625	0.95	CCR5 (0.42)	CCR5ROCK2ROCK1RAB9AGPR88
	SCHEMBL2563624	0.94	RAB9A (0.41)	CCR5ROCK2ROCK1RAB9AGPR88
	SCHEMBL2563596	0.90	ROCK2 (0.41)	CCR5ROCK2ROCK1RAB9AGPR88
	SCHEMBL2567782	0.87	CCR5 (0.40)	CCR5BDKRB1RAB9ANPC1FKBP1A
	SCHEMBL2564590	0.83	OPRK1 (0.48)	BDKRB1OPRM1OPRD1OPRK1
	SCHEMBL2570812	0.83	BDKRB1 (0.43)	BDKRB1RAB9ANPC1LMNA
	SCHEMBL492720	0.82	CACNA2D1 (0.36)	CCR5BDKRB1RAB9ANPC1ALDH1A1
	SCHEMBL14411636	0.82	RAB9A (0.42)	CCR5RAB9ANPC1FKBP1A
	SCHEMBL2568325	0.80	BDKRB1 (0.40)	BDKRB1ALDH1A1
	SCHEMBL2566106	0.80	MEN1 (0.52)	ALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.