Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.47 |
| ▸ | CPT1A | P50416 | 15/20 | 0.39 |
| ▸ | CPT2 | P23786 | 7/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CPT1B | Q92523 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28590672 | 0.77 | ALDH1A1 (0.54) | SCD5FAAH | |
| SCHEMBL6646886 | 0.75 | CPT1A (0.42) | SCD5CPT1ACPT2GRM5 | |
| SCHEMBL8237755 | 0.75 | CHRNB2 (0.45) | — | |
| SCHEMBL4220121 | 0.74 | PREP (0.50) | FAAH | |
| SCHEMBL23242847 | 0.71 | FAAH (0.38) | FAAH | |
| SCHEMBL7520129 | 0.71 | PRMT5 (0.53) | SCD5 | |
| SCHEMBL2571299 | 0.71 | ALDH1A1 (0.42) | GRM5 | |
| SCHEMBL14637214 | 0.71 | CPT1A (0.46) | CPT1ACPT2GRM5CPT1B | |
| SCHEMBL2042725 | 0.71 | PKM (0.50) | CPT1ACPT2CPT1B | |
| SCHEMBL16400185 | 0.71 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718279-A1 | NOVEL COMPOUNDS AS MODULATORS OF GPR-119 | Rhizen Pharmaceuticals S.A. (CH) | 2014-04-16 | — | — | EP | disclosed |
| EP-2555772-A1 | OXAZOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH | Merck Sharp & Dohme Corp. (US) | 2013-02-13 | — | — | EP | disclosed |
| WO-2012170867-A1 | NOVEL COMPOUNDS AS MODULATORS OF GPR-119 | RHIZEN PHARMACEUTICALS SA (CH) | 2012-12-13 | — | — | WO | disclosed |
| WO-2011126960-A1 | OXAZOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH | MERCK SHARP & DOHME CORP. (US) | 2011-10-13 | — | — | WO | disclosed |