Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.42 |
| ▸ | RORB | Q92753 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20286599 | 0.91 | ALOX5 (0.67) | ALOX5ADORA2AADORA1ADORA3HTT | |
| SCHEMBL168009 | 0.89 | ALOX5 (0.55) | ALOX5ADORA2AADORA1ADORA3HTT | |
| SCHEMBL4746033 | 0.87 | ALOX5 (0.62) | ALOX5ADORA2AADORA1ADORA3HTT | |
| SCHEMBL4746826 | 0.80 | ALOX5 (0.57) | ALOX5ADORA2AADORA1ADORA3HTT | |
| SCHEMBL168675 | 0.79 | RORB (0.46) | ALOX5LMNAMAPTPTGDR2RORB | |
| SCHEMBL8154046 | 0.78 | ALOX5 (0.52) | ALOX5ADORA2AADORA1ADORA3HTT | |
| SCHEMBL4746026 | 0.73 | ADORA2A (0.49) | ALOX5ADORA2AADORA1ADORA3HTT | |
| SCHEMBL169403 | 0.66 | RORC (0.58) | ADORA2AADORA1ADORA3HTTNPSR1 | |
| SCHEMBL20969597 | 0.66 | KARS1 (0.65) | HTTPPARGPPARALMNAMAPT | |
| SCHEMBL20969558 | 0.66 | KARS1 (0.65) | ALDH1A1PPARGPPARAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |