Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.58 |
| ▸ | RORB | Q92753 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | ATP4A | P20648 | 2/20 | 0.43 |
| ▸ | ATP4B | P51164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165773 | 0.80 | ADORA3 (0.61) | RORBALDH1A1HSD17B10ADORA2AADORA1 | |
| SCHEMBL168009 | 0.79 | ALOX5 (0.55) | RORCALDH1A1ADORA2AADORA1LMNA | |
| SCHEMBL257432 | 0.79 | RORB (0.74) | RORCRORBALDH1A1HSD17B10ADORA2A | |
| SCHEMBL174332 | 0.78 | SMN1; SMN2 (0.54) | RORBALDH1A1HSD17B10ADORA1LMNA | |
| SCHEMBL12496026 | 0.76 | ATP4A (0.47) | RORCRORBALDH1A1HSD17B10ATP4A | |
| SCHEMBL175512 | 0.76 | RORB (0.54) | RORCRORBALDH1A1HSD17B10ADORA2A | |
| SCHEMBL10092891 | 0.74 | RORC (1.00) | RORCRORB | |
| SCHEMBL19496819 | 0.74 | AOC3 (0.56) | ALDH1A1 | |
| SCHEMBL10092883 | 0.74 | RORB (0.67) | RORCRORBALDH1A1HSD17B10ADORA2A | |
| SCHEMBL27653923 | 0.73 | ALDH1A1 (0.64) | RORCRORBALDH1A1HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |