SCHEMBL2572076

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8207295	0.89	MMP1 (0.61)	TSHRMMP1MMP3MMP7MMP13
	SCHEMBL6977510	0.88	MMP1 (0.63)	TSHRKDM4EMMP1MMP3MMP7
	SCHEMBL8211716	0.85	RAB9A (0.59)	TSHRMMP1MMP3MMP7MMP13
	SCHEMBL6325815	0.85	RAB9A (0.59)	TSHRMMP1MMP3MMP7MMP13
	SCHEMBL2568316	0.84	MEN1 (0.52)	MEN1KMT2AL3MBTL1POLBPKM
	SCHEMBL3776857	0.80	CASP3 (0.48)	MEN1KMT2AL3MBTL1POLBPKM
	SCHEMBL12162069	0.80	NPC1 (0.60)	TSHRMMP1MMP3MMP7MMP13
	SCHEMBL13037004	0.78	PSEN1 (0.71)	KMT2APOLBPKMTSHRMMP1
	SCHEMBL8210424	0.78	TSHR (0.60)	KMT2AL3MBTL1TSHRMMP1MMP3
	SCHEMBL10795608	0.77	PSEN1 (0.59)	TSHRKDM4EPSEN1PSEN2APH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.