Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | EDNRA | P25101 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16319063 | 0.88 | L3MBTL1 (0.63) | MAPTL3MBTL1TDP1MAPK1RAB9A | |
| SCHEMBL978857 | 0.88 | HTT (0.64) | MAPTL3MBTL1LMNAPTGER1SMN1; SMN2 | |
| SCHEMBL410077 | 0.86 | PTGER1 (0.76) | MAPTL3MBTL1TDP1MAPK1PTGER1 | |
| SCHEMBL29930977 | 0.85 | SGMS2 (0.54) | MAPTL3MBTL1TDP1MAPK1RAB9A | |
| SCHEMBL1305662 | 0.85 | HPGD (0.57) | MAPTL3MBTL1TDP1MAPK1RAB9A | |
| SCHEMBL5940976 | 0.85 | SGMS2 (0.54) | MAPTL3MBTL1TDP1MAPK1RAB9A | |
| SCHEMBL1097551 | 0.85 | SGMS2 (0.54) | MAPTL3MBTL1TDP1MAPK1RAB9A | |
| SCHEMBL23611725 | 0.84 | NPC1 (0.60) | RAB9ALMNAPTGER1SMN1; SMN2SGMS2 | |
| SCHEMBL34466882 | 0.84 | L3MBTL1 (0.53) | MAPTL3MBTL1TDP1MAPK1RAB9A | |
| SCHEMBL29930885 | 0.84 | NPC1 (0.60) | RAB9ALMNAPTGER1SMN1; SMN2SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192629-A1 | METHODS OF SYNTHESIZING FARNESYL DIBENZODIAZEPINONES | AMO PHARMA LTD. (US) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192629-A1 | METHODS OF SYNTHESIZING FARNESYL DIBENZODIAZEPINONES | FNTB, FNTA, FDPS | MAPT 2499/4885L3MBTL1 3660/4885TDP1 3369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.