Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.34 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL256719 | 0.83 | TDP1 (0.41) | KDM4EPOLBCA12CA1CA2 | |
| SCHEMBL15100730 | 0.81 | POLB (0.43) | KDM4EPOLBTSHRHSD17B10ALDH1A1 | |
| SCHEMBL12164265 | 0.76 | KDM4E (0.55) | KDM4EPOLBTSHRALDH1A1MRGPRX4 | |
| SCHEMBL28599971 | 0.76 | TDP1 (0.50) | KDM4EPOLBCA12CA1CA2 | |
| SCHEMBL256737 | 0.75 | DCLRE1B (0.40) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL257679 | 0.74 | HCAR2 (0.39) | KDM4ETSHRALDH1A1DCLRE1ADCLRE1B | |
| SCHEMBL24801286 | 0.74 | APEX1 (0.44) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL9450687 | 0.74 | XDH (0.43) | KDM4EPOLBALDH1A1MRGPRX4SMN1; SMN2 | |
| SCHEMBL12197595 | 0.70 | KDM4E (0.49) | KDM4EPOLBCA12CA1CA2 | |
| SCHEMBL13981636 | 0.70 | PTPN1 (0.53) | KDM4ECA1CA2CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012029942-A1 | CYCLIC AMIDE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2012-03-08 | — | — | WO | disclosed |