Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.34 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257685 | 0.86 | ALDH1A1 (0.42) | TSHRALDH1A1KDM4ELMNA | |
| SCHEMBL256719 | 0.83 | TDP1 (0.41) | HCAR2TSHRALDH1A1KDM4EDCLRE1A | |
| SCHEMBL15100967 | 0.81 | KDM4E (0.45) | ALDH1A1PTGER4KDM4E | |
| SCHEMBL28622015 | 0.77 | LTB4R (0.47) | TSHRMAPK1ALDH1A1KDM4ELMNA | |
| SCHEMBL8245934 | 0.76 | FOLH1 (0.59) | TSHRMAPK1ALDH1A1KDM4EFOLH1 | |
| SCHEMBL256737 | 0.75 | DCLRE1B (0.40) | TSHRALDH1A1KDM4EFOLH1DCLRE1A | |
| SCHEMBL257240 | 0.74 | KDM4E (0.40) | TSHRALDH1A1PPARGPPARAKDM4E | |
| SCHEMBL24801286 | 0.74 | APEX1 (0.44) | TSHRALDH1A1KDM4EFOLH1DCLRE1A | |
| SCHEMBL17797893 | 0.73 | TSHR (0.46) | HCAR2TSHRMAPK1ALDH1A1PPARG | |
| SCHEMBL27760882 | 0.72 | HCAR2 (0.40) | HCAR2TSHRMAPK1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012029942-A1 | CYCLIC AMIDE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2012-03-08 | — | — | WO | disclosed |