Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | CES1 | P23141 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18692020 | 0.81 | ACHE (0.46) | CES2CES1ACHENFE2L2ALDH1A1 | |
| SCHEMBL2568052 | 0.81 | CES2 (0.43) | CES2CES1PDK2MEN1KMT2A | |
| SCHEMBL3792566 | 0.74 | ACHE (0.38) | CES2CES1ACHENFE2L2ALDH1A1 | |
| SCHEMBL8932025 | 0.74 | ACHE (0.43) | CES2CES1ACHENFE2L2NPC1 | |
| Boric Acid SCHEMBL29277889 | 0.72 | ACHE (0.37) | CES2CES1ACHENFE2L2ALDH1A1 | |
| SCHEMBL28217811 | 0.72 | ACHE (0.42) | CES2CES1ACHENFE2L2NPC1 | |
| SCHEMBL15091550 | 0.72 | ACHE (0.42) | CES2CES1ACHENFE2L2ALDH1A1 | |
| SCHEMBL29214133 | 0.71 | CES2 (0.41) | CES2CES1ACHEALDH1A1ALOX15 | |
| Bromide SCHEMBL19405493 | 0.70 | ACHE (0.35) | CES2CES1ACHENFE2L2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL19405604 | 0.70 | ACHE (0.35) | CES2CES1ACHENFE2L2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10620481-B2 | Optical alignment film composition, optical alignment film, optical laminate, and image display device | FUJIFILM CORPORATION (JP) | 2020-04-14 | — | — | US | disclosed |
| US-20180246381-A1 | OPTICAL ALIGNMENT FILM COMPOSITION, OPTICAL ALIGNMENT FILM, OPTICAL LAMINATE, AND IMAGE DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2018-08-30 | — | — | US | disclosed |
| US-8993470-B2 | Catalysts for the alkyne metathesis | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2015-03-31 | — | — | US | disclosed |
| EP-2556078-B1 | CATALYSTS FOR ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2014-09-24 | — | — | EP | disclosed |
| US-20130144102-A1 | CATALYSTS FOR THE ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2013-06-06 | — | — | US | disclosed |
| EP-2556078-A1 | CATALYSTS FOR ALKYNE METATHESIS | Studiengesellschaft Kohle MbH (DE) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011120508-A1 | CATALYSTS FOR ALKYNE METATHESIS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2011-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130144102-A1 | CATALYSTS FOR THE ALKYNE METATHESIS | MSH6, AP3M1, PMS2 | CES2 2740/4885CES1 4172/4885ACHE 1185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.