Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AHCY | P23526 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | ADA | P00813 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21011208 | 0.87 | HIF1A (0.38) | HIF1APOLBP2RY1 | |
| SCHEMBL21011356 | 0.85 | P2RX3 (0.45) | POLBP2RY1 | |
| SCHEMBL21011214 | 0.77 | HIF1A (0.64) | HIF1A | |
| SCHEMBL25752695 | 0.77 | HIF1A (0.64) | HIF1A | |
| SCHEMBL10446884 | 0.76 | ADA (0.55) | HIF1APOLBADORA3P2RY1ADA | |
| SCHEMBL25752677 | 0.75 | TK1 (0.37) | POLB | |
| SCHEMBL25752681 | 0.75 | HIF1A (0.37) | HIF1APOLBP2RY1 | |
| SCHEMBL25752702 | 0.74 | HIF1A (0.39) | HIF1A | |
| SCHEMBL22340126 | 0.72 | P2RX3 (0.49) | POLBP2RY1 | |
| SCHEMBL21011333 | 0.72 | P2RX3 (0.49) | POLBP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230175030-A1 | NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES | Nuclera Nucleics Ltd. (GB) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230175030-A1 | NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES | RNGTT, POLM, POLRMT | HIF1A 2566/4885POLB 5/4885AHCY 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.