Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGAV | P06756 | 2/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.35 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.35 |
| ▸ | ITGA8 | P53708 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24036755 | 0.92 | L3MBTL1 (0.42) | WDR5L3MBTL1POLBITGB3ITGAV | |
| SCHEMBL24036565 | 0.87 | WDR5 (0.37) | WDR5L3MBTL1POLBITGB3ITGAV | |
| SCHEMBL24036756 | 0.86 | POLB (0.38) | WDR5L3MBTL1POLBITGB3ITGAV | |
| SCHEMBL25754069 | 0.85 | POLB (0.39) | L3MBTL1POLBITGB3ITGAVITGB5 | |
| SCHEMBL25754000 | 0.83 | ITGB3 (0.37) | WDR5L3MBTL1ITGB3ITGAVITGB5 | |
| SCHEMBL25625380 | 0.82 | WDR5 (0.35) | WDR5L3MBTL1POLBLMNAITGB1 | |
| Hydrochloric Acid SCHEMBL30388430 | 0.82 | ITGB3 (0.37) | WDR5L3MBTL1ITGB3ITGAVITGB5 | |
| SCHEMBL24036731 | 0.82 | WDR5 (0.50) | WDR5PNPKMT2ATACR3ALDH1A1 | |
| SCHEMBL25625085 | 0.81 | THRB (0.36) | POLBITGB3ITGAVITGB5ITGB6 | |
| SCHEMBL24036821 | 0.81 | ITGB1 (0.40) | WDR5ITGB3ITGAVITGB5ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192661-A1 | 1, 4, 5, 6-TETRAHYDROPYRIMIDINE-2-AMINE DERIVATIVE | UBE CORPORATION (JP) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192661-A1 | 1, 4, 5, 6-TETRAHYDROPYRIMIDINE-2-AMINE DERIVATIVE | DHFR, DPYD, CYP2D6 | WDR5 2145/4885L3MBTL1 2036/4885POLB 860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.