Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25754649 | 0.87 | ALDH1A1 (0.40) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL20095668 | 0.69 | ALDH1A1 (0.60) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL25754621 | 0.69 | HRH3 (0.33) | — | |
| SCHEMBL25754561 | 0.68 | SIGMAR1 (0.41) | ALDH1A1 | |
| SCHEMBL25754557 | 0.68 | ACHE (0.35) | — | |
| SCHEMBL17552000 | 0.68 | HRH3 (0.48) | — | |
| SCHEMBL27840764 | 0.66 | ALDH1A1 (0.92) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL875207 | 0.66 | ALDH1A1 (0.92) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| Propane SCHEMBL1169005 | 0.64 | ALDH1A1 (0.75) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL18920437 | 0.64 | KDM4E (0.41) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | UCHL3, UBE2L3, ADAM33 | ALDH1A1 2539/4885HSD17B10 2815/4885THRB 646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.