SCHEMBL25754621

SCHEMBL25754621

CC#CCCN1CC(N2CCCCC2)C1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 9/20 0.33
SIGMAR1 Q99720 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17552000 0.78 HRH3 (0.48) HRH3
SCHEMBL25754561 0.77 SIGMAR1 (0.41) SIGMAR1
SCHEMBL18801053 0.72 SMN1; SMN2 (0.44)
SCHEMBL25754634 0.72
SCHEMBL15686294 0.70 ALOX15 (0.48) SIGMAR1
SCHEMBL4550278 0.70 SIGMAR1 (0.37) HRH3SIGMAR1
SCHEMBL25754631 0.69 ALDH1A1 (0.40)
Hydrochloric Acid SCHEMBL15664097 0.69 ALOX15 (0.46) SIGMAR1
SCHEMBL25754633 0.68 AGTR2 (0.36)
SCHEMBL3478510 0.68 SIGMAR1 (0.34) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 HRH3 1596/4885SIGMAR1 4773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.