Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 2/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21022111 | 0.81 | TGFBR1 (0.48) | TGFBR1MAPKAPK2 | |
| SCHEMBL28200272 | 0.80 | HDAC1 (0.50) | KIF11HDAC1ABL1BCRTRPV1 | |
| SCHEMBL16894177 | 0.80 | ABL1 (0.43) | ABL1BCRTGFBR1TRPV3 | |
| SCHEMBL28042873 | 0.80 | SCN10A (0.55) | KIF11ABL1BCRADORA3KDM2B | |
| SCHEMBL28074646 | 0.79 | TRPA1 (0.36) | KIF11HDAC1ABL1BCRTGFBR1 | |
| SCHEMBL27764812 | 0.79 | KIF11 (0.52) | KIF11HDAC1ABL1BCRTRPV1 | |
| SCHEMBL2161283 | 0.78 | ABL1 (0.55) | KIF11HDAC1ABL1BCRKDM1A | |
| SCHEMBL26739795 | 0.78 | ASIC3 (0.53) | TGFBR1MAPKAPK2 | |
| SCHEMBL16903663 | 0.77 | HDAC1 (0.46) | KIF11HDAC1ABL1BCRTRPV1 | |
| SCHEMBL30636782 | 0.76 | CCR1 (0.48) | TGFBR1MAPKAPK2CDK1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121184-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | disclosed |
| CN-105143188-A | Novel sulfonamide trpa1 receptor antagonists | PHARMESTE S R L IN LIQUIDATION | 2015-12-09 | — | — | CN | disclosed |